GABA-containing interneurons are crucial to both the development and function of the
cerebral cortex. Unlike cortical projection neurons, which have a relatively conserved set of …

The immense range of human behaviours is rooted in the complex neural networks of the
cerebrum. The creation of these networks depends on the precise integration of specific …

Cerebral cortical functions are conducted by two general classes of neurons: glutamatergic
projection neurons and GABAergic interneurons. Distinct interneuron subtypes serve distinct …

Null mutation of the Foxg1 gene causes hypoplasia of the mouse telencephalon and loss of
ventral telencephalic structures. We show that a crucial early requirement for Foxg1 is in the …

Neurosecretory control centers form part of the forebrain in many animal phyla, including
vertebrates, insects, and annelids. The evolutionary origin of these centers is largely …

Substitutive cell therapy using fetal striatal grafts has demonstrated preliminary clinical
success in patients with Huntington's disease, but the logistics required for accessing fetal …

GABAergic interneurons are inhibitory neurons of the nervous system that play a vital role in
neural circuitry and activity. They are so named due to their release of the neurotransmitter …

The homeodomain transcription factor Nkx2-1 plays key roles in the developing
telencephalon, where it regulates the identity of progenitor cells in the medial ganglionic …

Interneurons in the cerebral cortex regulate cortical functions through the actions of distinct
subgroups that express parvalbumin, somatostatin, or calretinin. The genesis of the first two …

Axonal connections between the left and right sides of the brain are crucial for bilateral
integration of lateralized sensory, motor, and associative functions. Throughout vertebrate …