Introduction EGFR-mutant NSCLC displays diverse outcomes to tyrosine kinase inhibitor
(TKI) treatment. Because co-occurring genomic alterations might describe different …

Background/Aim: A small subset of patients with ovarian clear cell carcinoma (OCCC)
harbors telomerase reverse transcriptase promoter (TERTp) mutations. We aimed to analyze …

Purpose Next-generation sequencing (NGS)-based tumor panel testing has been
reimbursed by the Korean government since 2017. We evaluated the use of NGS-based …

Next-generation sequencing (NGS) is becoming essential in the fields of precision oncology.
With implementation of NGS in daily clinic, the needs for continued education, facilitated …

Introduction: Treatment options for biliary tract cancer (BTC) are very limited. It is necessary
to investigate actionable genes and candidate drugs using a sophisticated knowledgebase …

Purpose This study investigated the clinical utility of next‐generation sequencing (NGS) for
detection of genetic alterations and its implications on treatment of lung adenocarcinoma in …

Comprehensive biomarker testing has become the standard of care for informing the choice
of the most appropriate targeted therapy for many patients with advanced cancer. Despite …

Aberrant DNA methylation plays a critical role in the development and progression of
colorectal cancer (CRC), which has high incidence and mortality rates in Korea. Various …

Purpose Homologous recombination deficiency (HRD), which influences the efficacy of
PARP inhibitor-and platinum agent-based therapies, is a prevalent phenotype of breast …

Background: Although next generation sequencing (NGS) has been adopted as an essential
diagnostic tool in various diseases, NGS errors have been the most serious problem in …