Advances in targeted therapy mainly based on signal pathways for nasopharyngeal carcinoma
Y Kang, W He, C Ren, J Qiao, Q Guo, J Hu… - Signal transduction and …, 2020 - nature.com
Nasopharyngeal carcinoma (NPC) is a malignant epithelial carcinoma of the head and neck
region which mainly distributes in southern China and Southeast Asia and has a crucial …
region which mainly distributes in southern China and Southeast Asia and has a crucial …
ORAI channels and cancer
SB Chalmers, GR Monteith - Cell calcium, 2018 - Elsevier
Cancer is a major cause of death. The diversity of cancer types and the propensity of
cancers to acquire resistance to therapies, including new molecularly targeted and immune …
cancers to acquire resistance to therapies, including new molecularly targeted and immune …
Comparative effect of sodium butyrate and sodium propionate on proliferation, cell cycle and apoptosis in human breast cancer cells MCF-7
Introduction Short-chain fatty acids (SCFAs) are ubiquitous lipids produced as a result of
bacterial fermentation of dietary fiber. While their role in colorectal cancer is well known, the …
bacterial fermentation of dietary fiber. While their role in colorectal cancer is well known, the …
Suppression of Stim1 reduced intracellular calcium concentration and attenuated hypoxia/reoxygenation induced apoptosis in H9C2 cells
F He, Q Wu, B Xu, X Wang, J Wu, L Huang… - Bioscience …, 2017 - portlandpress.com
Objective: Previous studies have demonstrated Stromal interaction molecule 1 (STIM1)-
mediated store-operated Ca2+ entry (SOCE) contributes to intracellular Ca2+ accumulation …
mediated store-operated Ca2+ entry (SOCE) contributes to intracellular Ca2+ accumulation …
β-carotene targets IP3R/GRP75/VDAC1-MCU axis to renovate LPS-induced mitochondrial oxidative damage by regulating STIM1
M Meng, Y Jiang, Y Wang, R Huo, N Ma, X Shen… - Free Radical Biology …, 2023 - Elsevier
Endoplasmic reticulum (ER) and mitochondria are the main sites for the storage and
regulation of Ca 2+ homeostasis. An imbalance of Ca 2+ homeostasis can cause ER stress …
regulation of Ca 2+ homeostasis. An imbalance of Ca 2+ homeostasis can cause ER stress …
[HTML][HTML] Sodium Butyrate (NaB) and Sodium Propionate (NaP) Reduce Cyclin A2 Expression, Inducing Cell Cycle Arrest and Proliferation Inhibition of Different Breast …
JN Ibrahim, S El-Hakim, J Semaan, S Ghosn… - Biomedicines, 2024 - mdpi.com
Sodium butyrate (NaB) and sodium propionate (NaP) have recently garnered attention for
their role in regulating inflammation and controlling signaling pathways of cell growth and …
their role in regulating inflammation and controlling signaling pathways of cell growth and …
β-carotene alleviates LPS-induced inflammation through regulating STIM1/ORAI1 expression in bovine mammary epithelial cells
M Meng, R Huo, N Ma, G Chang, X Shen - International …, 2022 - Elsevier
Abstract β-carotene has anti-inflammatory properties. STIM1 (Stromol interaction molecule
1)/ORAI1 (Orai calcium release-activated calcium modulator 1) is an important inflammatory …
1)/ORAI1 (Orai calcium release-activated calcium modulator 1) is an important inflammatory …
[HTML][HTML] Selenoprotein K deficiency inhibits melanoma by reducing calcium flux required for tumor growth and metastasis
Interest has emerged in the therapeutic potential of inhibiting store operated calcium (Ca 2+)
entry (SOCE) for melanoma and other cancers because malignant cells exhibit a strong …
entry (SOCE) for melanoma and other cancers because malignant cells exhibit a strong …
[HTML][HTML] Tetrandrine downregulates TRPV2 expression to ameliorate myocardial ischemia/reperfusion injury in rats via regulation of cardiomyocyte apoptosis, calcium …
L Jiang, X Zhou, X Zhao, Z Wang, A Huang… - European Journal of …, 2024 - Elsevier
Our previous study has indicated that tetrandrine (TET) can target miR-202-5p to repress the
activation of transient receptor potential vanilloid type 2 (TRPV2), eventually ameliorating …
activation of transient receptor potential vanilloid type 2 (TRPV2), eventually ameliorating …
Short-term stimulation with histone deacetylase inhibitor trichostatin a induces epithelial-mesenchymal transition in nasopharyngeal carcinoma cells without …
Z Shen, X Liao, Z Shao, M Feng, J Yuan, S Wang… - BMC cancer, 2019 - Springer
Background Epithelial-mesenchymal transition (EMT) may be one of the reasons for the
failure in some clinical trials regarding histone deacetylase inhibitors (HDACIs)-treated solid …
failure in some clinical trials regarding histone deacetylase inhibitors (HDACIs)-treated solid …