Small noncoding vault RNA2‐1 disrupts gut epithelial barrier function via interaction with HuR

XX Ma, L Xiao, SJ Wen, TX Yu, S Sharma… - EMBO …, 2023 - embopress.org
Vault RNAs (vtRNAs) are small noncoding RNAs and highly expressed in many eukaryotes.
Here, we identified vtRNA2‐1 as a novel regulator of the intestinal barrier via interaction with …

nc886, an RNA polymerase III-Transcribed noncoding RNA whose expression is dynamic and regulated by intriguing mechanisms

YS Lee, YS Lee - International Journal of Molecular Sciences, 2023 - mdpi.com
nc886 is a medium-sized non-coding RNA that is transcribed by RNA polymerase III (Pol III)
and plays diverse roles in tumorigenesis, innate immunity, and other cellular processes …

Emerging role of toll-like receptors signaling and its regulators in preterm birth: a narrative review

G Huang, D Yao, X Yan, M Zheng, P Yan… - Archives of Gynecology …, 2023 - Springer
Introduction Despite intensive research, preterm birth (PTB) rates have not decreased
significantly in recent years due to a lack of understanding of the underlying causes and …

Ambient air pollution during pregnancy and DNA methylation in umbilical cord blood, with potential mediation of associations with infant adiposity: the healthy start …

AP Starling, C Wood, C Liu, K Kechris, IV Yang… - Environmental …, 2022 - Elsevier
Background Prenatal exposure to ambient air pollution has been associated with adverse
offspring health outcomes. Childhood health effects of prenatal exposures may be mediated …

Development and validation of a prediction model on spontaneous preterm birth in twin pregnancy: a retrospective cohort study

X Yang, Q Zhong, L Li, Y Chen, C Tang, T Liu, S Luo… - Reproductive …, 2023 - Springer
Background This study was conducted to develop and validate an individualized prediction
model for spontaneous preterm birth (sPTB) in twin pregnancies. Methods This a …

[HTML][HTML] Vault RNAs (vtRNAs): Rediscovered non-coding RNAs with diverse physiological and pathological activities

MA Mir - Genes & Diseases, 2024 - Elsevier
The physicochemical characteristics of RNA admit non-coding RNAs to perform a different
range of biological acts through various mechanisms and are involved in regulating a …

The impact of DNA methylation as a factor of Adverse Pregnancy and Birth Outcomes (APBOs): a systematic review protocol

I Moagi, L Mabasa, SM Maputle, D Ndwandwe… - Systematic …, 2024 - Springer
Background Deoxyribonucleic acid (DNA) methylation is one of the epigenetic modifications
that has gained a lot of interest as a factor influencing fetal programming and as a biomarker …

Non-coding 886 (nc886/vtRNA2-1), the epigenetic odd duck – implications for future studies

E Raitoharju, S Rajić, S Marttila - Epigenetics, 2024 - Taylor & Francis
ABSTRACT Non-coding 886 (nc886, vtRNA2–1) is the only human polymorphically
imprinted gene, in which the methylation status is not determined by genetics. Existing …

[HTML][HTML] Noncoding Vault RNA1-1 Impairs Intestinal Epithelial Renewal and Barrier Function by Interacting with CUG-binding Protein 1

S Sharma, L Xiao, HK Chung, T Chen… - Cellular and Molecular …, 2024 - Elsevier
ABSTRACT BACKGROUND & AIMS Small noncoding vault RNAs (vtRNAs) are involved in
many cell processes important for health and disease, but their pathobiological functions in …

The mystique of epigenetic regulation: the remarkable case of a human noncoding RNA, nc886

YS Lee, YS Lee - Epigenomics, 2024 - Taylor & Francis
ABSTRACT nc886 is a regulatory noncoding RNA that is transcribed by RNA polymerase III
(Pol III), is variably expressed in different biological contexts, and plays roles in inflammation …