A. Cellular and Subcellular Localization B. Pharmacological Tools to Study Adenosine
Receptors C. Signaling Via Adenosine Receptors D. Regulation of Receptor Expression and …

This paper presents an overview of the current knowledge about the role of adenosine in the
sleep-wake regulation with a focus on adenosine in the central nervous system, regulation …

Caffeine, a component of tea, coffee and cola, induces wakefulness. It binds to adenosine
A1 and A2A receptors as an antagonist, but the receptor subtype mediating caffeine-induced …

Caffeine, the most widely consumed psychoactive drug, enhances attention/vigilance,
stabilizes mood, and might also independently enhance cognitive performance. Notably …

▪ Abstract Adenosine and its receptors have been the topic of many recent reviews (–).
These reviews provide a good summary of much of the relevant literature—including the …

Adenosine is a potent endogenous regulator of inflammation and tissue repair. Adenosine,
which is released from injured and hypoxic tissue or in response to toxins and medications …

Caffeine is the most consumed psychoactive drug worldwide and its intake in moderate
amounts prevents neurodegenerative disorders. However, the molecular targets of caffeine …

Prostaglandin (PG) D2 and adenosine are potent humoral sleep-inducing factors that
accumulate in the brain during prolonged wakefulness. PGD2 is produced in the brain by …

This chapter summarizes the current knowledge about the role of adenosine in the sleep–
wake regulation with a focus on adenosine in the brain, regulation of adenosine levels …

Pyrimidine and purine nucleosides and their derivatives have critical functions and
pharmacological applications in the brain. Nucleosides and nucleobases are precursors of …