Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages

JF Emile, O Abla, S Fraitag, A Horne… - Blood, The Journal …, 2016 - ashpublications.org
The histiocytoses are rare disorders characterized by the accumulation of macrophage,
dendritic cell, or monocyte-derived cells in various tissues and organs of children and adults …

Histiocytosis

JF Emile, F Cohen-Aubart, M Collin, S Fraitag, A Idbaih… - The Lancet, 2021 - thelancet.com
Histiocytoses constitute a heterogeneous group of rare disorders, characterised by
infiltration of almost any organ by myeloid cells with diverse macrophage or dendritic cell …

[HTML][HTML] Identification of diverse activating mutations of the RAS-MAPK pathway in histiocytic sarcoma

V Shanmugam, GK Griffin, ED Jacobsen… - Modern Pathology, 2019 - Elsevier
Recent studies have demonstrated recurrent activating mutations involving the classical
MAPK and PI3K signaling pathways in a large proportion of histiocytic neoplasms, such as …

[HTML][HTML] Genomic profiling of primary histiocytic sarcoma reveals two molecular subgroups

C Egan, A Nicolae, J Lack, HJ Chung… - …, 2020 - ncbi.nlm.nih.gov
Histiocytic sarcoma is a rare malignant neoplasm that may occur de novo or in the context of
a previous hematologic malignancy or mediastinal germ cell tumor. Here, we performed …

Treatment of Langerhans cell histiocytosis and histiocytic disorders: a focus on MAPK pathway inhibitors

AV Geerlinks, O Abla - Pediatric Drugs, 2023 - Springer
Histiocytic disorders are rare diseases defined by the clonal accumulation of a macrophage
or dendritic cell origin. These disorders include Langerhans cell histiocytosis, Erdheim …

No more tears for metal 3D printing

I Todd - Nature, 2017 - nature.com
No more tears for metal 3D printing | Nature Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …

Histiocytic and dendritic cell neoplasms: what have we learnt by studying 67 cases

F Facchetti, SA Pileri, L Lorenzi, V Tabanelli, L Rimsza… - Virchows Archiv, 2017 - Springer
Tumors derived from histiocytic and dendritic cells encompass a large and heterogeneous
group of neoplastic and reactive conditions, and their diagnosis is challenging both for …

Histiocytic sarcoma: review, discussion of transformation from B-cell lymphoma, and differential diagnosis

SL Skala, DR Lucas, R Dewar - Archives of pathology & …, 2018 - meridian.allenpress.com
Context.—Histiocytic sarcoma is a rare neoplasm of mature histiocytes with an aggressive
clinical course that can arise de novo or from a low-grade B-cell lymphoma. In particular …

BRAF mutation and its inhibitors in sarcoma treatment

H Liu, N Nazmun, S Hassan, X Liu, J Yang - Cancer Medicine, 2020 - Wiley Online Library
The mitogen‐activated protein kinase (MAPK) signaling pathway plays a significant role in
mediating cellular physiological activities, such as proliferation, differentiation, apoptosis …

Histiocytic sarcoma as a secondary malignancy: pathobiology, diagnosis, and treatment

J Ansari, AR Naqash, R Munker… - European journal of …, 2016 - Wiley Online Library
Histiocytic sarcoma (HS) is an extremely rare non‐Langerhans cell disorder with an
aggressive course and limited treatment options. Recent advances in molecular/genetic …