Hypothalamus‐pituitary‐thyroid axis
TM Ortiga‐Carvalho, MI Chiamolera… - Comprehensive …, 2011 - Wiley Online Library
The hypothalamus‐pituitary‐thyroid (HPT) axis determines the set point of thyroid hormone
(TH) production. Hypothalamic thyrotropin‐releasing hormone (TRH) stimulates the …
(TH) production. Hypothalamic thyrotropin‐releasing hormone (TRH) stimulates the …
[HTML][HTML] Perinatal exposure to glyphosate-based herbicide alters the thyrotrophic axis and causes thyroid hormone homeostasis imbalance in male rats
JS de Souza, MML Kizys, RR da Conceição… - Toxicology, 2017 - Elsevier
Glyphosate-based herbicides (GBHs) are widely used in agriculture. Recently, several
animal and epidemiological studies have been conducted to understand the effects of these …
animal and epidemiological studies have been conducted to understand the effects of these …
[HTML][HTML] T3/TRs axis in hepatocellular carcinoma: new concepts for an old pair
A Perra, M Plateroti… - Endocrine-Related …, 2016 - erc.bioscientifica.com
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide, and
its burden is expected to further increase in the next years. Chronic inflammation, induced by …
its burden is expected to further increase in the next years. Chronic inflammation, induced by …
HINT2 protects against pressure overload‐induced cardiac remodelling through mitochondrial pathways
N Zhang, ZY Zhou, YY Meng, HH Liao… - Journal of Cellular …, 2024 - Wiley Online Library
Histidine triad nucleotide‐binding protein 2 (HINT2) is an enzyme found in mitochondria that
functions as a nucleotide hydrolase and transferase. Prior studies have demonstrated that …
functions as a nucleotide hydrolase and transferase. Prior studies have demonstrated that …
Partial Resistance to Thyroid Hormone–Induced Tachycardia and Cardiac Hypertrophy in Mice Lacking Thyroid Hormone Receptor β
Background: Thyroid hormones regulate cardiac functions mainly through direct actions in
the heart and by binding to the thyroid hormone receptor (TR) isoforms α1 and β. While the …
the heart and by binding to the thyroid hormone receptor (TR) isoforms α1 and β. While the …
[HTML][HTML] Qiliqiangxin attenuates phenylephrine-induced cardiac hypertrophy through downregulation of MiR-199a-5p
H Zhang, S Li, Q Zhou, Q Sun, S Shen, Y Zhou… - Cellular Physiology and …, 2016 - karger.com
Background/Aims: Qiliqiangxin (QL), a traditional Chinese medicine, has long been used to
treat chronic heart failure. Previous studies demonstrated that QL could prevent cardiac …
treat chronic heart failure. Previous studies demonstrated that QL could prevent cardiac …
Chiral toxicity of muscone to embryonic zebrafish heart
M Li, L Yao, H Chen, X Ni, Y Xu, W Dong, M Fang… - Aquatic toxicology, 2020 - Elsevier
Musk compounds are often used as to treat heart-related diseases and are widely used in
Asia. Muscone is one of the most important physiologically active compounds of natural …
Asia. Muscone is one of the most important physiologically active compounds of natural …
Regeneration of Thyroid Glands in the Spleen Restores Homeostasis in Thyroidectomy Mice
XJ Tian, ZJ Yin, ZJ Li, ZZ Wang, Z Xing… - Advanced …, 2024 - Wiley Online Library
Surgical removal of the thyroid gland (TG) for treating thyroid disorders leaves the patients
on lifelong hormone replacement that partially compensates the physiological needs, but …
on lifelong hormone replacement that partially compensates the physiological needs, but …
Canonical and noncanonical contribution of thyroid hormone receptor isoforms alpha and beta to cardiac hypertrophy and heart rate in male mice
D Geist, GS Hönes, SC Grund, J Pape, D Siemes… - Thyroid, 2024 - liebertpub.com
Background: Stimulation of ventricular hypertrophy and heart rate are two major cardiac
effects of thyroid hormone (TH). The aim of this study was to determine in vivo which TH …
effects of thyroid hormone (TH). The aim of this study was to determine in vivo which TH …
Thyroid hormone induces restrictive cardiomyopathy in β1-adrenoceptor knockout mice
The purpose of this study was to characterize the role of β1-AR signaling and its cross-talk
between cardiac renin–angiotensin system and thyroid-hormone-induced cardiac …
between cardiac renin–angiotensin system and thyroid-hormone-induced cardiac …