Serotonin and brain function: a tale of two receptors
RL Carhart-Harris, DJ Nutt - Journal of psychopharmacology, 2017 - journals.sagepub.com
Previous attempts to identify a unified theory of brain serotonin function have largely failed to
achieve consensus. In this present synthesis, we integrate previous perspectives with new …
achieve consensus. In this present synthesis, we integrate previous perspectives with new …
Reviewing the potential of psychedelics for the treatment of PTSD
E Krediet, T Bostoen, J Breeksema… - International Journal …, 2020 - academic.oup.com
There are few medications with demonstrated efficacy for the treatment of posttraumatic
stress disorder (PTSD). Treatment guidelines have unequivocally designated psychotherapy …
stress disorder (PTSD). Treatment guidelines have unequivocally designated psychotherapy …
[HTML][HTML] MDMA-assisted therapy for moderate to severe PTSD: a randomized, placebo-controlled phase 3 trial
This multi-site, randomized, double-blind, confirmatory phase 3 study evaluated the efficacy
and safety of 3, 4-methylenedioxymethamphetamine-assisted therapy (MDMA-AT) versus …
and safety of 3, 4-methylenedioxymethamphetamine-assisted therapy (MDMA-AT) versus …
MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study
Post-traumatic stress disorder (PTSD) presents a major public health problem for which
currently available treatments are modestly effective. We report the findings of a randomized …
currently available treatments are modestly effective. We report the findings of a randomized …
[HTML][HTML] Distinct acute effects of LSD, MDMA, and d-amphetamine in healthy subjects
Lysergic acid diethylamide (LSD) is a classic psychedelic, 3, 4-
methylenedioxymethamphetamine (MDMA) is an empathogen, and d-amphetamine is a …
methylenedioxymethamphetamine (MDMA) is an empathogen, and d-amphetamine is a …
Acute effects of lysergic acid diethylamide in healthy subjects
Y Schmid, F Enzler, P Gasser, E Grouzmann… - Biological …, 2015 - Elsevier
Background After no research in humans for> 40 years, there is renewed interest in using
lysergic acid diethylamide (LSD) in clinical psychiatric research and practice. There are no …
lysergic acid diethylamide (LSD) in clinical psychiatric research and practice. There are no …
[HTML][HTML] MDMA-assisted psychotherapy for treatment of anxiety and other psychological distress related to life-threatening illnesses: a randomized pilot study
PE Wolfson, J Andries, AA Feduccia, L Jerome… - Scientific reports, 2020 - nature.com
The success of modern medicine creates a growing population of those suffering from life-
threatening illnesses (LTI) who often experience anxiety, depression, and existential …
threatening illnesses (LTI) who often experience anxiety, depression, and existential …
[HTML][HTML] Breakthrough for trauma treatment: safety and efficacy of MDMA-assisted psychotherapy compared to paroxetine and sertraline
AA Feduccia, L Jerome, B Yazar-Klosinski… - Frontiers in …, 2019 - frontiersin.org
Unsuccessfully treated posttraumatic stress disorder (PTSD) is a serious and life-threatening
disorder. Two medications, paroxetine hydrochloride and sertraline hydrochloride, are …
disorder. Two medications, paroxetine hydrochloride and sertraline hydrochloride, are …
[HTML][HTML] LSD acutely impairs fear recognition and enhances emotional empathy and sociality
Lysergic acid diethylamide (LSD) is used recreationally and has been evaluated as an
adjunct to psychotherapy to treat anxiety in patients with life-threatening illness. LSD is well …
adjunct to psychotherapy to treat anxiety in patients with life-threatening illness. LSD is well …
3, 4-Methylenedioxymethamphetamine-assisted psychotherapy for treatment of chronic posttraumatic stress disorder: a randomized phase 2 controlled trial
M Ot'alora G, J Grigsby, B Poulter… - Journal of …, 2018 - journals.sagepub.com
Background: Posttraumatic stress disorder often does not resolve after conventional
psychotherapies or pharmacotherapies. Pilot studies have reported that 3, 4 …
psychotherapies or pharmacotherapies. Pilot studies have reported that 3, 4 …