Advanced glycation end products (AGEs) and their receptor have been implicated in the
progressions of many intractable diseases, such as diabetes and atherosclerosis, and are …

Cross-talk between adipose tissue and central nervous system (CNS) underlies the
increased risk of obese people to develop brain diseases such as cognitive and mood …

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common and
potentially lethal clinical syndromes characterized by acute respiratory failure resulting from …

Introduction Neuroinflammation and autophagy are implicated in stress-related major
depressive disorder (MDD), but the underlying molecular mechanisms remain largely …

Adiponectin, as an indispensable regulator of the immune system, is the most abundant
adipokine and is mainly produced by white adipose tissue. Adiponectin mediates the …

Animal and human mechanistic studies have consistently shown an association between
obesity and Alzheimer's disease (AD). AD, a degenerative brain disease, is the most …

Aims Secreted factors produced by adipose tissue are involved in the pathogenesis of
cardiovascular disease. We previously identified adipolin, also known as C1q/TNF-related …

Alzheimer's disease (AD), characterized by the abnormal accumulation of amyloid beta (Aβ),
is gradually increasing globally. Given that AD is considered a neuroinflammatory disease …

Due to the progressive increase in the incidence of obese and overweight individuals,
cardiometabolic syndrome has become a worldwide pandemic in recent years. Given the …

Gastrodin (GAS), the main phenolic glycoside extracted from Gastrodia elata Blume, exhibits
potential renoprotective properties. Here, we examined the protective effects of GAS on …