Genetically encoded fluorescent biosensors illuminate the spatiotemporal regulation of signaling networks

EC Greenwald, S Mehta, J Zhang - Chemical reviews, 2018 - ACS Publications
Cellular signaling networks are the foundation which determines the fate and function of
cells as they respond to various cues and stimuli. The discovery of fluorescent proteins over …

Carbon monoxide and its controlled release: therapeutic application, detection, and development of carbon monoxide releasing molecules (CORMs) miniperspective

K Ling, F Men, WC Wang, YQ Zhou… - Journal of Medicinal …, 2017 - ACS Publications
Carbon monoxide (CO) is attracting increasing attention because of its role as a
gasotransmitter with cytoprotective and homeostatic properties. Carbon monoxide releasing …

Recent progress in fluorescent probes for detection of carbonyl species: Formaldehyde, carbon monoxide and phosgene

X Liu, N Li, M Li, H Chen, N Zhang, Y Wang… - Coordination Chemistry …, 2020 - Elsevier
Extensive attention has been paid to develop effective systems for the detection of
formaldehyde, carbon monoxide and phosgene due to their extreme toxicity and ready …

Carbon monoxide–physiology, detection and controlled release

SH Heinemann, T Hoshi, M Westerhausen… - Chemical …, 2014 - pubs.rsc.org
Carbon monoxide (CO) is increasingly recognized as a cell-signalling molecule akin to nitric
oxide (NO). CO has attracted particular attention as a potential therapeutic agent because of …

Carbon‐monoxide‐releasing molecules for the delivery of therapeutic CO in vivo

S García‐Gallego… - Angewandte Chemie …, 2014 - Wiley Online Library
The development of carbon‐monoxide‐releasing molecules (CORMs) as pharmaceutical
agents represents an attractive and safer alternative to administration of gaseous CO. Most …

Biological signaling by carbon monoxide and carbon monoxide-releasing molecules

R Motterlini, R Foresti - American Journal of Physiology …, 2017 - journals.physiology.org
Carbon monoxide (CO) is continuously produced in mammalian cells during the
degradation of heme. It is a stable gaseous molecule that reacts selectively with transition …

Two-photon luminescent metal complexes for bioimaging and cancer phototherapy

Y Chen, R Guan, C Zhang, J Huang, L Ji… - Coordination Chemistry …, 2016 - Elsevier
Possessing important advantages over conventional one-photon excited emission such as
great depth discrimination and reduced photo-damage, two-photon excited emission (TPE) …

Novel lead structures and activation mechanisms for CO‐releasing molecules (CORMs)

U Schatzschneider - British journal of pharmacology, 2015 - Wiley Online Library
Carbon monoxide (CO) is an endogenous small signalling molecule in the human body,
produced by the action of haem oxygenase on haem. Since it is very difficult to apply safely …

A reaction-based fluorescent probe for imaging of formaldehyde in living cells

A Roth, H Li, C Anorma, J Chan - Journal of the American …, 2015 - ACS Publications
Formaldehyde (FA), in the 0.2–0.4 mM range, is produced and maintained endogenously
via enzymatic pathways. At these levels, FA can promote cell proliferation as well as mediate …

A minimalist fluorescent probe for differentiating Cys, Hcy and GSH in live cells

H Zhang, R Liu, J Liu, L Li, P Wang, SQ Yao, Z Xu… - Chemical …, 2016 - pubs.rsc.org
A simple molecule, tetrafluoroterephthalonitrile (4F-2CN), was discovered to be an efficient
fluorescent probe for detecting biological thiol species. The probe responded to Cys and …