Although gray matter (GM) damages caused by long term and excessive alcohol
consumption have long been reported, the structural neuroimaging findings on alcohol-use …

Rationale While stress is often proposed to play a significant role in influencing alcohol
consumption, the relationship between stress and alcohol is complex and poorly …

Patients with alcohol use disorder (AUD) present with important emotional, cognitive, and
social impairments. The gut microbiota has been recently shown to regulate brain functions …

Midbrain dopamine neurons are an essential component of the basal ganglia circuitry,
playing key roles in the control of fine movement and reward. Recently, it has been …

Recent evidence supports the influence of neuroimmune system activation on behavior. We
have demonstrated that ethanol activates the innate immune system by stimulating toll-like …

Family, twin and adoption studies demonstrate clearly that alcohol dependence and alcohol
use disorders are phenotypically complex and heritable. The heritability of alcohol use …

Excessive alcohol consumption is one of the main causes of death and disability worldwide.
Alcohol consumption is a heritable complex trait. Here we conducted a meta-analysis of …

Repeated cycles of binge alcohol drinking and abstinence are key components in the
development of dependence. However, the precise behavioral mechanisms underlying …

Emerging evidence demonstrates that alcohol dependence is associated with dysregulation
of several neurotransmitters. Alterations in dopamine, glutamate and gamma-aminobutyric …

Emerging evidence indicates that dysfunctional glutamate neurotransmission is critical in the
initiation and development of alcohol and drug dependence. Alcohol consumption induced …