Protective effect of curcumin against heavy metals-induced liver damage

WR García-Niño, J Pedraza-Chaverrí - Food and chemical toxicology, 2014 - Elsevier
Occupational or environmental exposures to heavy metals produce several adverse health
effects. The common mechanism determining their toxicity and carcinogenicity is the …

Genotoxic and epigenetic mechanisms in arsenic carcinogenicity

E Bustaffa, A Stoccoro, F Bianchi, L Migliore - Archives of toxicology, 2014 - Springer
Arsenic is a human carcinogen with weak mutagenic properties that induces tumors through
mechanisms not yet completely understood. People worldwide are exposed to arsenic …

Environmental chemicals and microRNAs

L Hou, D Wang, A Baccarelli - Mutation Research/Fundamental and …, 2011 - Elsevier
MicroRNAs (miRNAs) are short single-stranded non-coding molecules that function as
negative regulators to silence or suppress gene expression. Aberrant miRNA expression …

Dietary flavonoids as cancer prevention agents

H Yao, W Xu, X Shi, Z Zhang - Journal of Environmental Science …, 2011 - Taylor & Francis
Dietary agents identified from fruits and vegetables contribute to keeping balanced cell
proliferation and preventing cell carcinogenesis. Dietary flavonoids, combined with other …

Flavonoids and stilbenoids as a promising arsenal for the management of chronic arsenic toxicity

A Mishra, P Oliinyk, R Lysiuk, L Lenchyk… - Environmental …, 2022 - Elsevier
Rapid industrial and technological development has impacted ecosystem homeostasis
strongly. Arsenic is one of the most detrimental environmental toxins and its management …

Natural compounds that target DNA repair pathways and their therapeutic potential to counteract cancer cells

FA Lagunas-Rangel, RM Bermúdez-Cruz - Frontiers in Oncology, 2020 - frontiersin.org
Resistance to current cancer treatments is an important problem that arises through various
mechanisms, but one that stands out involves an overexpression of several factors …

Resveratrol attenuates hepatotoxicity of rats exposed to arsenic trioxide

W Zhang, J Xue, M Ge, M Yu, L Liu, Z Zhang - Food and Chemical …, 2013 - Elsevier
Arsenic trioxide (As2O3) is an environmental pollutant and potent toxicant to humans.
However, it also shows substantial anti-cancer activity in individuals with acute …

Curcumin ameliorates oxaliplatin‐induced chemoresistance in HCT116 colorectal cancer cells in vitro and in vivo

LM Howells, S Sale, SN Sriramareddy… - … journal of cancer, 2011 - Wiley Online Library
The aims of this study were to determine potency of oxaliplatin in combination with curcumin
in oxaliplatin‐resistant cell lines in vitro and to evaluate the efficacy of a novel curcumin …

[HTML][HTML] Targeting the DNA damage response (DDR) of cancer cells with natural compounds derived from Panax ginseng and other plants

SG Choi, M Shin, WY Kim - Journal of Ginseng Research, 2024 - Elsevier
DNA damage is a driver of cancer formation, leading to the impairment of repair
mechanisms in cancer cells and rendering them susceptible to DNA-damaging therapeutic …

Nrf2-mediated redox signaling in arsenic carcinogenesis: a review

D Sinha, J Biswas, A Bishayee - Archives of toxicology, 2013 - Springer
Arsenic is a ubiquitous toxic metalloid whose natural leaching from geogenic resources of
earths crust into groundwater has become a dreadful health hazard to millions of people …