Protective effect of curcumin against heavy metals-induced liver damage
WR García-Niño, J Pedraza-Chaverrí - Food and chemical toxicology, 2014 - Elsevier
Occupational or environmental exposures to heavy metals produce several adverse health
effects. The common mechanism determining their toxicity and carcinogenicity is the …
effects. The common mechanism determining their toxicity and carcinogenicity is the …
Genotoxic and epigenetic mechanisms in arsenic carcinogenicity
Arsenic is a human carcinogen with weak mutagenic properties that induces tumors through
mechanisms not yet completely understood. People worldwide are exposed to arsenic …
mechanisms not yet completely understood. People worldwide are exposed to arsenic …
Environmental chemicals and microRNAs
L Hou, D Wang, A Baccarelli - Mutation Research/Fundamental and …, 2011 - Elsevier
MicroRNAs (miRNAs) are short single-stranded non-coding molecules that function as
negative regulators to silence or suppress gene expression. Aberrant miRNA expression …
negative regulators to silence or suppress gene expression. Aberrant miRNA expression …
Dietary flavonoids as cancer prevention agents
H Yao, W Xu, X Shi, Z Zhang - Journal of Environmental Science …, 2011 - Taylor & Francis
Dietary agents identified from fruits and vegetables contribute to keeping balanced cell
proliferation and preventing cell carcinogenesis. Dietary flavonoids, combined with other …
proliferation and preventing cell carcinogenesis. Dietary flavonoids, combined with other …
Flavonoids and stilbenoids as a promising arsenal for the management of chronic arsenic toxicity
Rapid industrial and technological development has impacted ecosystem homeostasis
strongly. Arsenic is one of the most detrimental environmental toxins and its management …
strongly. Arsenic is one of the most detrimental environmental toxins and its management …
Natural compounds that target DNA repair pathways and their therapeutic potential to counteract cancer cells
FA Lagunas-Rangel, RM Bermúdez-Cruz - Frontiers in Oncology, 2020 - frontiersin.org
Resistance to current cancer treatments is an important problem that arises through various
mechanisms, but one that stands out involves an overexpression of several factors …
mechanisms, but one that stands out involves an overexpression of several factors …
Resveratrol attenuates hepatotoxicity of rats exposed to arsenic trioxide
W Zhang, J Xue, M Ge, M Yu, L Liu, Z Zhang - Food and Chemical …, 2013 - Elsevier
Arsenic trioxide (As2O3) is an environmental pollutant and potent toxicant to humans.
However, it also shows substantial anti-cancer activity in individuals with acute …
However, it also shows substantial anti-cancer activity in individuals with acute …
Curcumin ameliorates oxaliplatin‐induced chemoresistance in HCT116 colorectal cancer cells in vitro and in vivo
LM Howells, S Sale, SN Sriramareddy… - … journal of cancer, 2011 - Wiley Online Library
The aims of this study were to determine potency of oxaliplatin in combination with curcumin
in oxaliplatin‐resistant cell lines in vitro and to evaluate the efficacy of a novel curcumin …
in oxaliplatin‐resistant cell lines in vitro and to evaluate the efficacy of a novel curcumin …
[HTML][HTML] Targeting the DNA damage response (DDR) of cancer cells with natural compounds derived from Panax ginseng and other plants
SG Choi, M Shin, WY Kim - Journal of Ginseng Research, 2024 - Elsevier
DNA damage is a driver of cancer formation, leading to the impairment of repair
mechanisms in cancer cells and rendering them susceptible to DNA-damaging therapeutic …
mechanisms in cancer cells and rendering them susceptible to DNA-damaging therapeutic …
Nrf2-mediated redox signaling in arsenic carcinogenesis: a review
D Sinha, J Biswas, A Bishayee - Archives of toxicology, 2013 - Springer
Arsenic is a ubiquitous toxic metalloid whose natural leaching from geogenic resources of
earths crust into groundwater has become a dreadful health hazard to millions of people …
earths crust into groundwater has become a dreadful health hazard to millions of people …