Small cell lung cancer (SCLC) is an aggressive malignancy characterized by rapid
proliferation, early dissemination, acquired therapy resistance, and poor prognosis. Early …

Current treatment guidelines refer to small cell lung cancer (SCLC), one of the deadliest
human malignancies, as a homogeneous disease. Accordingly, SCLC therapy comprises …

Small cell lung cancer (SCLC) is a recalcitrant neuroendocrine carcinoma with dismal
survival outcomes. A major barrier in the field has been the relative paucity of human tumors …

Small cell lung cancer (SCLC) remains the most fatal form of lung cancer, with patients in
dire need of new and effective therapeutic approaches. Modeling SCLC in an …

Small cell lung cancer (SCLC) is an epithelial neuroendocrine form of lung cancer for which
survival rates remain dismal and new therapeutic approaches are greatly needed. Key …

The understanding of small cell lung cancer (SCLC) biology has increased dramatically in
recent years, but the processes that allow SCLC to progress rapidly remain poorly …

Simple Summary The heterogeneous expression of signaling molecules within the tumor,
including kinases, is the major contributor to the acquisition of drug resistance and poor …

Cancers arise through acquisition of mutations in genes that regulate core biological
processes like cell proliferation and cell death. Decades of cancer research have led to the …

Lung cancer is an extremely aggressive and highly prevalent disease worldwide, and it is
one of the leading causes of cancer death. Deciphering intrinsic genetic mechanism, finding …

Simple Summary Lung cancer is one of the leading cancers worldwide, with a poor
prognosis and high mortality. Recent studies show that epigenetic mechanisms such as …