Hydrogels and scaffolds for immunomodulation
For over two decades, immunologists and biomaterials scientists have co‐existed in parallel
world with the rationale of understanding the molecular profile of immune responses to …
world with the rationale of understanding the molecular profile of immune responses to …
Vaccination into the dermal compartment: techniques, challenges, and prospects
J Hettinga, R Carlisle - Vaccines, 2020 - mdpi.com
In 2019, an 'influenza pandemic'and 'vaccine hesitancy'were listed as two of the top 10
challenges to global health by the WHO. The skin is a unique vaccination site, due to its …
challenges to global health by the WHO. The skin is a unique vaccination site, due to its …
Recent advances and future perspectives in polymer-based nanovaccines
Vaccination is the most valuable and cost-effective health measure to prevent and control
the spread of infectious diseases. A significant number of infectious diseases and chronic …
the spread of infectious diseases. A significant number of infectious diseases and chronic …
Recent insights into cutaneous immunization: How to vaccinate via the skin
Technologies and strategies for cutaneous vaccination have been evolving significantly
during the past decades. Today, there is evidence for increased efficacy of cutaneously …
during the past decades. Today, there is evidence for increased efficacy of cutaneously …
Transcutaneous immunization using a dissolving microneedle array protects against tetanus, diphtheria, malaria, and influenza
K Matsuo, S Hirobe, Y Yokota, Y Ayabe, M Seto… - Journal of controlled …, 2012 - Elsevier
Transcutaneous immunization (TCI) is an attractive alternative vaccination route compared
to the commonly used injection systems. We previously developed a dissolving microneedle …
to the commonly used injection systems. We previously developed a dissolving microneedle …
Transdermal immunomodulation: Principles, advances and perspectives
Immunomodulation, manipulation of the immune responses towards an antigen, is a
promising strategy to treat cancer, infectious diseases, allergies, and autoimmune diseases …
promising strategy to treat cancer, infectious diseases, allergies, and autoimmune diseases …
A low-invasive and effective transcutaneous immunization system using a novel dissolving microneedle array for soluble and particulate antigens
K Matsuo, Y Yokota, Y Zhai, YS Quan… - Journal of controlled …, 2012 - Elsevier
Transcutaneous immunization (TCI) is a promising needle-free, easy-to-use, and low-
invasive vaccination method. The hydrogel patch-based TCI system induced immune …
invasive vaccination method. The hydrogel patch-based TCI system induced immune …
Applications and perspectives of nanomaterials in novel vaccine development
Y Shen, T Hao, S Ou, C Hu, L Chen - MedChemComm, 2018 - pubs.rsc.org
Vaccines show great potential for both prophylactic and therapeutic use in infections,
cancer, and other diseases. With the rapid development of bio-technologies and materials …
cancer, and other diseases. With the rapid development of bio-technologies and materials …
Performance and characteristics evaluation of a sodium hyaluronate-based microneedle patch for a transcutaneous drug delivery system
Y Hiraishi, T Nakagawa, YS Quan, F Kamiyama… - International journal of …, 2013 - Elsevier
The MicroHyala® microneedle (MN) patch was developed to provide a simple, safe, and
effective drug delivery system. In this study, we examined the performance and …
effective drug delivery system. In this study, we examined the performance and …
Polymeric hydrogel based systems for vaccine delivery: A review
The appropriate delivery of vaccines is a significant factor for the proper immunization. The
proper delivery of the cargo vaccine/antigen along with stimulation of high antigen mediated …
proper delivery of the cargo vaccine/antigen along with stimulation of high antigen mediated …