Advances in Babesia Vaccine Development: An Overview
M Jerzak, A Gandurski, M Tokaj, W Stachera, M Szuba… - Pathogens, 2023 - mdpi.com
Babesiosis is a tick-borne zoonotic disease, which is caused by various species of
intracellular Babesia parasite. It is a problem not only for the livestock industry but also for …
intracellular Babesia parasite. It is a problem not only for the livestock industry but also for …
A vaccine for human babesiosis: Prospects and feasibility
Babesiosis is a tick-borne disease caused by intraerythrocytic Babesia parasites. It is a well-
known illness in companion animals and livestock, resulting in substantial economic losses …
known illness in companion animals and livestock, resulting in substantial economic losses …
Kinetics of the invasion and egress processes of Babesia divergens, observed by time-lapse video microscopy
E Sevilla, LM González, D Luque, J Gray, E Montero - Scientific Reports, 2018 - nature.com
Based on confocal fluorescence and bright field video microscopy, we present detailed
observations on the processes of invasion and egress of erythrocytes by the apicomplexan …
observations on the processes of invasion and egress of erythrocytes by the apicomplexan …
[HTML][HTML] A library of recombinant Babesia microti cell surface and secreted proteins for diagnostics discovery and reverse vaccinology
CM Elton, M Rodriguez, CB Mamoun, CA Lobo… - International journal for …, 2019 - Elsevier
Human babesiosis is an emerging tick-borne parasitic disease and blood transfusion-
transmitted infection primarily caused by the apicomplexan parasite, Babesia microti. There …
transmitted infection primarily caused by the apicomplexan parasite, Babesia microti. There …
Babesia bovis RON2 contains conserved B-cell epitopes that induce an invasion-blocking humoral immune response in immunized cattle
Background Babesia bovis belongs to the phylum Apicomplexa and is the major causal
agent of bovine babesiosis, the most important veterinary disease transmitted by arthropods …
agent of bovine babesiosis, the most important veterinary disease transmitted by arthropods …
Evidence for vesicle-mediated antigen export by the human pathogen Babesia microti
J Thekkiniath, N Kilian, L Lawres… - Life Science …, 2019 - life-science-alliance.org
The apicomplexan parasite Babesia microti is the primary agent of human babesiosis, a
malaria-like illness and potentially fatal tick-borne disease. Unlike its close relatives, the …
malaria-like illness and potentially fatal tick-borne disease. Unlike its close relatives, the …
A conserved protein of Babesia microti elicits partial protection against Babesia and Plasmodium infection
Y Wang, Q Zhang, W Zhang, J Chen, J Dai, X Zhou - Parasites & Vectors, 2023 - Springer
Abstract Background The protozoan parasite Babesia microti that causes the zoonotic
disease babesiosis resides in the erythrocytes of its mammalian host during its life-cycle. No …
disease babesiosis resides in the erythrocytes of its mammalian host during its life-cycle. No …
Babesia bovis RON2 binds to bovine erythrocytes through a highly conserved epitope
L Cuy-Chaparro, D Barney-Borrero… - Veterinary …, 2024 - Elsevier
B. bovis invasion of bovine erythrocytes requires tight junction formation involving AMA-
1/RON2 complex interaction. RON2 has been considered a vaccine candidate since …
1/RON2 complex interaction. RON2 has been considered a vaccine candidate since …
Babesia microti Protein BmSP44 Is a Novel Protective Antigen in a Mouse Model of Babesiosis
H Wang, Y Wang, J Huang, B Xu, J Chen… - Frontiers in …, 2020 - frontiersin.org
Babesiosis caused by Babesia species imposes an increasing threat to public-health and so
far, there is no effective vaccine to prevent Babesia infections. Babesia surface antigen may …
far, there is no effective vaccine to prevent Babesia infections. Babesia surface antigen may …
RON2, a novel gene in Babesia bigemina, contains conserved, immunodominant B-cell epitopes that induce antibodies that block merozoite invasion
J Mosqueda, M Hidalgo-Ruiz, DA Calvo-Olvera… - Parasitology, 2019 - cambridge.org
Bovine babesiosis is the most important protozoan disease transmitted by ticks. In
Plasmodium falciparum, another Apicomplexa protozoan, the interaction of rhoptry neck …
Plasmodium falciparum, another Apicomplexa protozoan, the interaction of rhoptry neck …