[HTML][HTML] A comprehensive review of microneedles: Types, materials, processes, characterizations and applications
FK Aldawood, A Andar, S Desai - Polymers, 2021 - mdpi.com
Drug delivery through the skin offers many advantages such as avoidance of hepatic first-
pass metabolism, maintenance of steady plasma concentration, safety, and compliance over …
pass metabolism, maintenance of steady plasma concentration, safety, and compliance over …
[HTML][HTML] Bone tissue engineering in the treatment of bone defects
N Xue, X Ding, R Huang, R Jiang, H Huang, X Pan… - Pharmaceuticals, 2022 - mdpi.com
Bones play an important role in maintaining exercise and protecting organs. Bone defect, as
a common orthopedic disease in clinics, can cause tremendous damage with long treatment …
a common orthopedic disease in clinics, can cause tremendous damage with long treatment …
Microneedle array systems for long-acting drug delivery
The development of microneedles (MNs) assisted drug delivery technologies have been
highly active for more than two decades. The minimally invasive and self-administered MN …
highly active for more than two decades. The minimally invasive and self-administered MN …
[HTML][HTML] Microneedle arrays as transdermal and intradermal drug delivery systems: Materials science, manufacture and commercial development
E Larrañeta, REM Lutton, AD Woolfson… - Materials Science and …, 2016 - Elsevier
Transdermal drug delivery offers a number of advantages for the patient, due not only its non-
invasive and convenient nature, but also factors such as avoidance of first pass metabolism …
invasive and convenient nature, but also factors such as avoidance of first pass metabolism …
The role of 3D printing technology in microengineering of microneedles
Microneedles (MNs) are minimally invasive devices, which have gained extensive interest
over the past decades in various fields including drug delivery, disease diagnosis …
over the past decades in various fields including drug delivery, disease diagnosis …
Microneedles for drug and vaccine delivery
Microneedles were first conceptualized for drug delivery many decades ago, but only
became the subject of significant research starting in the mid-1990's when microfabrication …
became the subject of significant research starting in the mid-1990's when microfabrication …
Approaches for breaking the barriers of drug permeation through transdermal drug delivery
Transdermal drug delivery system (TDDS) utilizes the skin as executable route for drug
administration but the foremost barrier against drug permeability is the stratum corneum and …
administration but the foremost barrier against drug permeability is the stratum corneum and …
Microneedles for intradermal and transdermal drug delivery
TM Tuan-Mahmood, MTC McCrudden… - European Journal of …, 2013 - Elsevier
The formidable barrier properties of the uppermost layer of the skin, the stratum corneum,
impose significant limitations for successful systemic delivery of broad range of therapeutic …
impose significant limitations for successful systemic delivery of broad range of therapeutic …
[HTML][HTML] Microneedle mediated transdermal delivery of protein, peptide and antibody based therapeutics: current status and future considerations
M Kirkby, ARJ Hutton, RF Donnelly - Pharmaceutical research, 2020 - Springer
The success of protein, peptide and antibody based therapies is evident-the
biopharmaceuticals market is predicted to reach $388 billion by 2024 [1], and more than half …
biopharmaceuticals market is predicted to reach $388 billion by 2024 [1], and more than half …
Progress and perspective of microneedle system for anti-cancer drug delivery
Transdermal drug delivery exhibited encouraging prospects, especially through superficial
drug administration routes. However, only a few limited lipophilic drug molecules could …
drug administration routes. However, only a few limited lipophilic drug molecules could …