Abstract Significance: 8-Hydroxy-2-deoxyguanosine (8-OHdG) is generated after the repair
of ROS-mediated DNA damages and, thus, is one of the most widely recognized biomarkers …

Background Carotid artery atherosclerotic stenosis is a preventable major cause of stroke,
but there is still a need for definition of high-risk plaque in asymptomatic patients who might …

Background: Uric acid (UA) concentration within carotid plaque and its association with
cerebrovascular events have not been detected or quantified. Systemically, serum UA is a …

Purpose To examine associations of matrix metalloproteinase-9 (MMP-9) and monocyte
chemoattractant protein-1 (MCP-1) concentrations with the severity of carotid …

Uric acid is a marker of inflammation and a risk factor for atherosclerosis that has been
suggested to play a role in carotid plaque instability. Reduced atherosclerotic plaque …

Stroke is a leading cause of morbidity and mortality worldwide, and characterization of
vulnerable carotid plaque remains the spearhead of scientific research. Plaque …

Background Atherosclerosis is a chronic lipid-driven inflammatory disease with infiltration of
low-density lipoprotein and is considered as the pivotal step in plaque formation. The aim of …

Results: Individuals with an FMD value of≥ 8.8% had significantly higher blood
concentrations of antioxidative vitamins and lower concentrations of 8-oxodG in their urine …

Introduction. Oxidative stress plays an important role in atherosclerosis, but numerous
clinical trials have not confirmed a favourable effect of antioxidant supplementation. We …

Abstract Background/Objectives: The generation of reactive oxygen species (ROS) plays a
relevant role in the pathogenesis of atherosclerosis and of cardiovascular disease (CVD) …