The endothelium is a dynamic, semipermeable layer lining all blood vessels, regulating
blood vessel formation and barrier function. Proper composition and function of the …

Traumatic spinal cord injury (SCI) is a complex pathological process. The initial mechanical
damage is followed by a progressive secondary injury cascade. The injury ruptures the local …

We recently demonstrated that when mice are exposed to chronic mild hypoxia (CMH, 8% O
2), blood vessels in the spinal cord show transient vascular leak that is associated with …

Hypoxic preconditioning reduces disease severity in a mouse model of multiple sclerosis
(MS), in part by enhancing the barrier properties of spinal cord blood vessels. Because other …

Neural stem cell (NSCs) transplantation has been one of the hot topics in the repair of spinal
cord injury (SCI). Fibroblast growth factor (FGF) is considered a promising nerve injury …

Blood vessels in the central nervous system (CNS) are unique in having high electrical
resistance and low permeability, which creates a selective barrier protecting sensitive neural …

Chronic hypobaric hypoxia in high‐altitude areas is closely related to the occurrence of
many neurological diseases. Among these diseases, epilepsy is a common disease of the …

Spinal cord injury (SCI) often leads to cell death, vascular disruption, axonal signal
interruption, and permanent functional damage. Currently, there are no clearly effective …

Cerebrovascular microcirculation is essential for maintaining the physiological functions of
the brain. The brain can be protected from stress injury by remodeling the microcirculation …

Cell-based transplantation strategies possess great potential for spinal cord injury (SCI)
repair. Basic fibroblast growth factor (bFGF) has been reported to have multiple neuro …