Previous studies that have investigated the potential of in vivo abnormal α‐synuclein
deposits as a pathological biomarker for PD included few participants and reported different …

In Parkinson's disease (PD), neuronal alpha‐synuclein aggregates are distributed
throughout the nervous system, including the brain, spinal cord, sympathetic ganglia …

Neuronal aggregates of misfolded alpha-synuclein protein are found in the brain and
periphery of patients with Parkinson's disease. Braak and colleagues have hypothesized …

The proximity ligation assay (PLA) is a specific and sensitive technique for the detection of
αSyn oligomers (αSyn-PLA), early and toxic species implicated in the pathogenesis of PD …

Parkinson's disease (PD) is a common neurodegenerative disease characterized
pathologically by dopaminergic neuron loss and the formation of Lewy bodies, which are …

A variety of cellular processes, including vesicle clustering in the presynaptic compartment,
are impaired in Parkinson's disease and have been closely associated with α-synuclein …

There are currently no standardized therapies for Parkinson disease (PD). Curcumin shows
anti-amyloidogenic properties in vitro and may be a promising treatment for PD. We …

Parkinson's disease (PD) is a neurodegenerative disorder associated with the death of
dopaminergic neurons within the substantia nigra of the brain. Melanoma is a cancer of …

The possible usefulness of alpha-synuclein (aSyn) determinations in peripheral tissues
(blood cells, salivary gland biopsies, olfactory mucosa, digestive tract, skin) and in biological …

Parkinson's disease is associated with a variety of dermatologic disorders and the study of
skin may provide insights into pathophysiological mechanisms underlying this common …