New developments in RiPP discovery, enzymology and engineering
M Montalbán-López, TA Scott, S Ramesh… - Natural product …, 2021 - pubs.rsc.org
Covering: up to June 2020 Ribosomally-synthesized and post-translationally modified
peptides (RiPPs) are a large group of natural products. A community-driven review in 2013 …
peptides (RiPPs) are a large group of natural products. A community-driven review in 2013 …
The amazing potential of fungi: 50 ways we can exploit fungi industrially
Fungi are an understudied, biotechnologically valuable group of organisms. Due to the
immense range of habitats that fungi inhabit, and the consequent need to compete against a …
immense range of habitats that fungi inhabit, and the consequent need to compete against a …
antiSMASH 7.0: new and improved predictions for detection, regulation, chemical structures and visualisation
Microorganisms produce small bioactive compounds as part of their secondary or
specialised metabolism. Often, such metabolites have antimicrobial, anticancer, antifungal …
specialised metabolism. Often, such metabolites have antimicrobial, anticancer, antifungal …
antiSMASH 6.0: improving cluster detection and comparison capabilities
K Blin, S Shaw, AM Kloosterman… - Nucleic acids …, 2021 - academic.oup.com
Many microorganisms produce natural products that form the basis of antimicrobials,
antivirals, and other drugs. Genome mining is routinely used to complement screening …
antivirals, and other drugs. Genome mining is routinely used to complement screening …
antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline
K Blin, S Shaw, K Steinke, R Villebro… - Nucleic acids …, 2019 - academic.oup.com
Secondary metabolites produced by bacteria and fungi are an important source of
antimicrobials and other bioactive compounds. In recent years, genome mining has seen …
antimicrobials and other bioactive compounds. In recent years, genome mining has seen …
A new genomic blueprint of the human gut microbiota
The composition of the human gut microbiota is linked to health and disease, but knowledge
of individual microbial species is needed to decipher their biological roles. Despite …
of individual microbial species is needed to decipher their biological roles. Despite …
Fungal secondary metabolism: regulation, function and drug discovery
NP Keller - Nature Reviews Microbiology, 2019 - nature.com
One of the exciting movements in microbial sciences has been a refocusing and
revitalization of efforts to mine the fungal secondary metabolome. The magnitude of …
revitalization of efforts to mine the fungal secondary metabolome. The magnitude of …
MGnify: the microbiome sequence data analysis resource in 2023
L Richardson, B Allen, G Baldi… - Nucleic Acids …, 2023 - academic.oup.com
Abstract The MGnify platform (https://www. ebi. ac. uk/metagenomics) facilitates the
assembly, analysis and archiving of microbiome-derived nucleic acid sequences. The …
assembly, analysis and archiving of microbiome-derived nucleic acid sequences. The …
A new antibiotic selectively kills Gram-negative pathogens
The current need for novel antibiotics is especially acute for drug-resistant Gram-negative
pathogens,. These microorganisms have a highly restrictive permeability barrier, which limits …
pathogens,. These microorganisms have a highly restrictive permeability barrier, which limits …
Review on natural products databases: where to find data in 2020
M Sorokina, C Steinbeck - Journal of cheminformatics, 2020 - Springer
Natural products (NPs) have been the centre of attention of the scientific community in the
last decencies and the interest around them continues to grow incessantly. As a …
last decencies and the interest around them continues to grow incessantly. As a …