Toxicity of ionic liquids: eco (cyto) activity as complicated, but unavoidable parameter for task‐specific optimization

KS Egorova, VP Ananikov - ChemSusChem, 2014 - Wiley Online Library
Rapid progress in the field of ionic liquids in recent decades led to the development of many
outstanding energy‐conversion processes, catalytic systems, synthetic procedures, and …

Recent advances in the applications of ionic liquids in protein stability and activity: a review

R Patel, M Kumari, AB Khan - Applied biochemistry and biotechnology, 2014 - Springer
Room temperatures ionic liquids are considered as miraculous solvents for biological
system. Due to their inimitable properties and large variety of applications, they have been …

Enzyme stability and activity in non-aqueous reaction systems: a mini review

S Wang, X Meng, H Zhou, Y Liu, F Secundo, Y Liu - Catalysts, 2016 - mdpi.com
Enormous interest in biocatalysis in non-aqueous phase has recently been triggered due to
the merits of good enantioselectivity, reverse thermodynamic equilibrium, and no water …

Room temperature ionic liquids meet biomolecules: a microscopic view of structure and dynamics

A Benedetto, P Ballone - ACS Sustainable Chemistry & …, 2016 - ACS Publications
Room temperature ionic liquids (RTILs) and biomolecules are both paradigmatic classes of
organic molecules, each consisting of a prodigious number of distinct chemical species …

Alternative excipients for protein stabilization in protein therapeutics: overcoming the limitations of polysorbates

AJ Castañeda Ruiz, MA Shetab Boushehri, T Phan… - Pharmaceutics, 2022 - mdpi.com
Given their safety and efficiency in protecting protein integrity, polysorbates (PSs) have been
the most widely used excipients for the stabilization of protein therapeutics for years. In …

Biocompatibility of ionic liquids towards protein stability: A comprehensive overview on the current understanding and their implications

A Kumar, M Bisht, P Venkatesu - International journal of biological …, 2017 - Elsevier
Over the past years since the discovery of ionic liquids (ILs), there is an increased demand
to consider ILs as novel biocompatible co-solvents for proteins. Due to their tunable physical …

Aqueous ionic liquids and their effects on protein structures: an overview on recent theoretical and experimental results

J Smiatek - Journal of Physics: Condensed Matter, 2017 - iopscience.iop.org
Ionic liquids (ILs) are used in a variety of technological and biological applications. Recent
experimental and simulation results reveal the influence of aqueous ionic liquids on the …

Effect of 1-methyl-3-octyleimmidazolium chloride on the stability and activity of lysozyme: a spectroscopic and molecular dynamics studies

M Kumari, N Dohare, N Maurya… - Journal of …, 2017 - Taylor & Francis
Herein, the binding of 1-methyl-3-octylimidazolium chloride [OMIM][Cl] ionic liquid with hen
egg white lysozyme (HEWL) has been studied using fluorescence, time resolved …

Molecular investigation of the interaction between ionic liquid type gemini surfactant and lysozyme: A spectroscopic and computational approach

JK Maurya, MUH Mir, UK Singh, N Maurya… - …, 2015 - Wiley Online Library
Herein, we are reporting the interaction of ionic liquid type gemini surfactant, 1, 4‐bis (3‐
dodecylimidazolium‐1‐yl) butane bromide ([C12− 4‐C12im] Br2) with lysozyme by using …

Mechanisms of Biological Effects of Ionic Liquids: From Single Cells to Multicellular Organisms

KS Egorova, AV Kibardin, AV Posvyatenko… - Chemical …, 2024 - ACS Publications
The review presents a detailed discussion of the evolving field studying interactions
between ionic liquids (ILs) and biological systems. Originating from molten salt electrolytes …