The immunological balance between host and parasite in malaria

K Deroost, TT Pham, G Opdenakker… - FEMS microbiology …, 2016 - academic.oup.com
Coevolution of humans and malaria parasites has generated an intricate balance between
the immune system of the host and virulence factors of the parasite, equilibrating maximal …

Long noncoding RNAs in innate immunity

Y Zhang, X Cao - Cellular & molecular immunology, 2016 - nature.com
Long noncoding RNAs (lncRNAs) have been shown to play important roles in immune cell
development and immune responses through different mechanisms, such as dosage …

Novel insights into the role of long non-coding RNA in the human malaria parasite, Plasmodium falciparum

G Batugedara, XM Lu, B Hristov, S Abel… - Nature …, 2023 - nature.com
The complex life cycle of Plasmodium falciparum requires coordinated gene expression
regulation to allow host cell invasion, transmission, and immune evasion. Increasing …

Single-cell RNA-seq reveals hidden transcriptional variation in malaria parasites

AJ Reid, AM Talman, HM Bennett, AR Gomes… - elife, 2018 - elifesciences.org
Single-cell RNA-sequencing is revolutionising our understanding of seemingly
homogeneous cell populations but has not yet been widely applied to single-celled …

[HTML][HTML] Chemical approaches to discover the full potential of peptide nucleic acids in biomedical applications

N Brodyagin, M Katkevics, V Kotikam… - Beilstein journal of …, 2021 - beilstein-journals.org
Peptide nucleic acid (PNA) is arguably one of the most successful DNA mimics, despite a
most dramatic departure from the native structure of DNA. The present review summarizes …

A specific PfEMP1 is expressed in P. falciparum sporozoites and plays a role in hepatocyte infection

G Zanghì, SS Vembar, S Baumgarten, S Ding… - Cell reports, 2018 - cell.com
Heterochromatin plays a central role in the process of immune evasion, pathogenesis, and
transmission of the malaria parasite Plasmodium falciparum during blood stage infection …

Changes in genome organization of parasite-specific gene families during the Plasmodium transmission stages

EM Bunnik, KB Cook, N Varoquaux… - Nature …, 2018 - nature.com
The development of malaria parasites throughout their various life cycle stages is
coordinated by changes in gene expression. We previously showed that the three …

ZFPM2-AS1, a novel lncRNA, attenuates the p53 pathway and promotes gastric carcinogenesis by stabilizing MIF

F Kong, X Deng, X Kong, Y Du, L Li, H Zhu, Y Wang… - Oncogene, 2018 - nature.com
Long non-coding RNAs (lncRNAs) are implicated to be involved in the pathogenesis of
many cancers. Herein we report on our discovery of a novel lncRNA, ZFPM2 antisense RNA …

Emerging biology of noncoding RNAs in malaria parasites

K Simantov, M Goyal, R Dzikowski - PLoS pathogens, 2022 - journals.plos.org
In eukaryotic organisms, noncoding RNAs (ncRNAs) have been implicated as important
regulators of multifaceted biological processes, including transcriptional, posttranscriptional …

Variant gene expression and antigenic variation by malaria parasites

KW Deitsch, R Dzikowski - Annual review of microbiology, 2017 - annualreviews.org
Malaria is a significant threat throughout the developing world. Among the most fascinating
aspects of the protozoan parasites responsible for this disease are the methods they employ …