Stem cell therapy for sequestration of traumatic brain injury-induced inflammation

MC Borlongan, S Rosi - International journal of molecular sciences, 2022 - mdpi.com
Traumatic brain injury (TBI) is one of the leading causes of long-term neurological
disabilities in the world. TBI is a signature disease for soldiers and veterans, but also affects …

The role of substance P within traumatic brain injury and implications for therapy

A Safwat, A Helmy, A Gupta - Journal of Neurotrauma, 2023 - liebertpub.com
This review examines the role of the neuropeptide substance P within the
neuroinflammation that follows traumatic brain injury. It examines it in reference to its …

Serum tau protein elevation in migraine: a cross-sectional case–control study

LH Overeem, B Raffaelli, R Fleischmann… - The Journal of …, 2023 - Springer
Background Migraine is a disorder associated with neuropeptide release, pain and
inflammation. Tau protein has recently been linked to inflammatory diseases and can be …

Chronic traumatic encephalopathy (CTE)—Features and forensic considerations

R Byard, M Tiemensma, ME Buckland… - Forensic Science, Medicine …, 2023 - Springer
Chronic traumatic encephalopathy (CTE) is a neurodegenerative condition, in which the
only known cause is exposure to repeated episodes of blunt head trauma. It most often …

Blast-induced neurotrauma results in spatially distinct gray matter alteration alongside hormonal alteration: a preliminary investigation

SC Hellewell, DA Granger, I Cernak - International Journal of Molecular …, 2023 - mdpi.com
Blast-induced neurotrauma (BINT) frequently occurs during military training and deployment
and has been linked to long-term neuropsychological and neurocognitive changes, and …

Effects of a neurokinin-1 receptor antagonist in the acute phase after thoracic spinal cord injury in a rat model

G Zheng, AK Harms, M Tail, H Zhang… - Frontiers in Molecular …, 2023 - frontiersin.org
Objective Disruption of the blood-spinal cord barrier (BSCB) with subsequent edema
formation and further neuroinflammation contributes to aggravation of spinal cord injury …

Correcting a widespread error: Neuroprotectant N-acetyl-L-tryptophan does not bind to the neurokinin-1 receptor

J Matalińska, PFJ Lipiński - Molecular and Cellular Neuroscience, 2022 - Elsevier
Abstract N-acetyl-L-tryptophan (NAT) has been often shown to have neuroprotective action
and other biological activities. In many of papers devoted to this compound, NAT is …

Individualized high-resolution analysis to categorize diverse learning and memory deficits in tau rTg4510 mice exposed to low-intensity blast

A Zuckerman, HR Siedhoff, A Balderrama… - Frontiers in Cellular …, 2024 - frontiersin.org
Mild traumatic brain injury (mTBI) resulting from low-intensity blast (LIB) exposure in military
and civilian individuals is linked to enduring behavioral and cognitive abnormalities. These …

Evidence for the involvement of the Tachykinin NK1 Receptor in Acute Inflammation of the Central Nervous System

RJ Turner, AJ Nimmo - Receptors, 2023 - mdpi.com
Neuroinflammation is considered to be a significant component in a range of
neuropathologies. Unfortunately, whilst its role is well recognised, the options for therapeutic …

Bidirectional regulation of the brain–gut–microbiota axis following traumatic brain injury

X You, L Niu, J Fu, S Ge, J Shi, Y Zhang… - Neural Regeneration …, 2025 - journals.lww.com
Traumatic brain injury is a prevalent disorder of the central nervous system. In addition to
primary brain parenchymal damage, the enduring biological consequences of traumatic …