Mechanistic understanding from molecular dynamics simulation in pharmaceutical research 1: drug delivery

A Bunker, T Róg - Frontiers in Molecular Biosciences, 2020 - frontiersin.org
In this review, we outline the growing role that molecular dynamics simulation is able to play
as a design tool in drug delivery. We cover both the pharmaceutical and computational …

Molecular interpretation of pharmaceuticals' adsorption on carbon nanomaterials: theory meets experiments

D Veclani, M Tolazzi, A Melchior - Processes, 2020 - mdpi.com
The ability of carbon-based nanomaterials (CNM) to interact with a variety of pharmaceutical
drugs can be exploited in many applications. In particular, they have been studied both as …

Insights into the adsorption mechanism of tetracycline on hierarchically porous carbon and the effect of nanoporous geometry

Y Wang, L Xu, F Wei, T Ding, M Zhang, R Zhu - Chemical Engineering …, 2022 - Elsevier
Hierarchically porous carbons (HPCs) have been shown to be effective adsorbents for
removing emerging pollutants such as antibiotics from water. To clarify the mechanisms of …

Adsorption and encapsulation of the drug doxorubicin on covalent functionalized carbon nanotubes: A scrutinized study by using molecular dynamics simulation and …

A Kordzadeh, S Amjad-Iranagh, M Zarif… - Journal of Molecular …, 2019 - Elsevier
Adsorption of the drug doxorubicin (DOX) onto covalent functionalized carbon nanotubes
(CNTs) as drug carriers was studied by employing molecular dynamics (MD) simulation …

The functionalization of carbon nanotubes to enhance the efficacy of the anticancer drug paclitaxel: a molecular dynamics simulation study

H Hashemzadeh, H Raissi - Journal of Molecular Modeling, 2017 - Springer
Carbon nanotubes (CNTs) are widely used in drug delivery systems (DDSs) due to their
unique chemical and physical properties. Investigation of interactions between biomolecules …

Investigation of the pristine and functionalized carbon nanotubes as a delivery system for the anticancer drug dacarbazine: drug encapsulation

H Mirsalari, A Maleki, H Raissi, A Soltanabadi - Journal of Pharmaceutical …, 2021 - Elsevier
Abstract Carbon Nanotubes (CNTs) have been used as the systems in drug delivery due to
their exceptional physical and chemical properties. In this study, the adsorption of an …

Functionalization of single and multi-walled carbon nanotubes with polypropylene glycol decorated pyrrole for the development of doxorubicin nano-conveyors for …

C Pennetta, G Floresta, ACE Graziano, V Cardile… - Nanomaterials, 2020 - mdpi.com
A recently reported functionalization of single and multi-walled carbon nanotubes, based on
a cycloaddition reaction between carbon nanotubes and a pyrrole derived compound, was …

Molecular dynamics simulation study of doxorubicin adsorption on functionalized carbon nanotubes with folic acid and tryptophan

T Arabian, S Amjad-Iranagh, R Halladj - Scientific reports, 2021 - nature.com
In this work, molecular dynamics (MD) simulation is used to study the adsorption of the
anticancer drug, doxorubicin (DOX), on the wall or surface of pristine and functionalized …

Facial synthesis of an efficient magnetic composite adsorbent using multiwalled carbon nanotubes and frankincense resin for the removal of amoxicillin …

SS Hussaini, M Hussain, M Asim, A Al-Balushi… - Journal of Molecular …, 2023 - Elsevier
We developed a new composite material (Fr@ MMWCNTs) consisting of multi-walled
carbon nanotubes (MWCNTs) and frankincense gum (Fr-gum) functionalized with magnetic …

Predicting doxorubicin drug delivery by single-walled carbon nanotube through cell membrane in the absence and presence of nicotine molecules: a molecular …

M Pakdel, H Raissi, M Shahabi - Journal of Biomolecular Structure …, 2020 - Taylor & Francis
In order to study the interaction of the anticancer agent Doxorubicin with the single-walled
carbon nanotubes with different diameters as drug delivery systems, the molecular dynamics …