This paper provides a critical review of several possible mechanisms at different levels of
analysis underlying the effects and therapeutic potential of psychedelics. At the (1) …

Rationale A broad reassessment of the potential benefits of psychedelic drugs has led to the
initiation of multiple major clinical trials in an effort to advance their status to become FDA …

Modern psychedelic research remains in an early phase, and the eventual introduction of
psychedelics into clinical practice remains in doubt. In this piece, we discuss the role of …

The acute subjective effects of psychedelics are responsive to users' expectations and
surroundings (ie,“set and setting”). Accordingly, a great deal of thought has gone into …

The administration of classic psychedelics has been associated with well-being and mental
health benefits as well as risks and adverse events. The acute subjective effects of …

Anticipating a renaissance, many psychedelic medicine companies have conducted initial
public offerings, whereinprivatecompaniesfirstissuenewshar… for sale to the public, making …

Background: Psilocybin-containing mushrooms are used for recreational, spiritual, self-
development and therapeutic purposes. However, physiologically relatively nontoxic …

Classic psychedelics and related substances have shown promising initial research results.
However, they raise a number of relatively novel ethical and policy challenges in light of …

Psychedelic research is proceeding rapidly, despite ongoing legal and regulatory barriers
and lingering questions about study design, such as the difficulty of ensuring adequate …

New medicines containing classic hallucinogenic and entactogenic psychedelic substance
are under development for various psychiatric and neurological disorders. Many of these …