Antifungal drugs: New insights in research & development

AM Nicola, P Albuquerque, HC Paes… - Pharmacology & …, 2019 - Elsevier
The need for better antifungal therapy is commonly accepted in view of the high mortality
rates associated with systemic infections, the low number of available antifungal classes …

[HTML][HTML] Fungal vaccines, mechanism of actions and immunology: A comprehensive review

S Nami, R Mohammadi, M Vakili, K Khezripour… - Biomedicine & …, 2019 - Elsevier
Fungal infections include a wide range of opportunistic and invasive diseases. Two of four
major fatal diseases in patients with human immunodeficiency virus (HIV) infection are …

Application of anti-fungal vaccines as a tool against emerging anti-fungal resistance

R Kumar, V Srivastava - Frontiers in Fungal Biology, 2023 - frontiersin.org
After viruses and bacteria, fungal infections remain a serious threat to the survival and well-
being of society. The continuous emergence of resistance against commonly used anti …

Recent insights into microbial triggers of interleukin-10 production in the host and the impact on infectious disease pathogenesis

BL Duell, CK Tan, AJ Carey, F Wu… - FEMS Immunology & …, 2012 - academic.oup.com
Since its initial description as a Th2-cytokine antagonistic to interferon-alpha and
granulocyte-macrophage colony-stimulating factor, many studies have shown various anti …

Recombinant Attenuated Salmonella enterica as a Delivery System of Heterologous Molecules in Cancer Therapy

EI Becerra-Báez, SE Meza-Toledo, P Muñoz-López… - Cancers, 2022 - mdpi.com
Simple Summary Cancer is among the main causes of death of millions of individuals
worldwide. Although survival has improved with conventional treatments, the appearance of …

Mucosal vaccines: novel strategies and applications for the control of pathogens and tumors at mucosal sites

M Nizard, MO Diniz, H Roussel, T Tran… - Human vaccines & …, 2014 - Taylor & Francis
The mucosal immune system displays several adaptations reflecting the exposure to the
external environment. The efficient induction of mucosal immune responses also requires …

Fungal vaccine development: State of the art and perspectives using Immunoinformatics

MM Inácio, ALE Moreira, VRM Cruz-Leite, K Mattos… - Journal of Fungi, 2023 - mdpi.com
Fungal infections represent a serious global health problem, causing damage to health and
the economy on the scale of millions. Although vaccines are the most effective therapeutic …

FungalRV: adhesin prediction and immunoinformatics portal for human fungal pathogens

R Chaudhuri, FA Ansari, MV Raghunandanan… - BMC genomics, 2011 - Springer
Background The availability of sequence data of human pathogenic fungi generates
opportunities to develop Bioinformatics tools and resources for vaccine development …

Immunity to fungi and vaccine considerations

AJ Whitehead, T Woodring, BS Klein - Cell Host & Microbe, 2024 - cell.com
Fungal disease poses a growing threat to public health that our current antifungal therapies
are not well equipped to meet. As the population of immunocompromised hosts expands …

Antibodies to Combat Fungal Infections: Development Strategies and Progress

AA Rabaan, AH Alfaraj, A Alshengeti, A Alawfi… - Microorganisms, 2023 - mdpi.com
The finding that some mAbs are antifungal suggests that antibody immunity may play a key
role in the defense of the host against mycotic infections. The discovery of antibodies that …