Vaccine Development Against Leishmania donovani

A Das, N Ali - Frontiers in immunology, 2012 - frontiersin.org
Visceral leishmaniasis (VL) caused by Leishmania donovani and Leishmania
infantum/chagasi represents the second most challenging infectious disease worldwide …

New approaches and omics tools for mining of vaccine candidates against vector-borne diseases

J Kuleš, A Horvatić, N Guillemin, A Galan… - Molecular …, 2016 - pubs.rsc.org
Vector-borne diseases (VBDs) present a major threat to human and animal health, as well
as place a substantial burden on livestock production. As a way of sustainable VBD control …

Essential proteins and possible therapeutic targets of Wolbachia endosymbiont and development of FiloBase-a comprehensive drug target database for Lymphatic …

OP Sharma, MS Kumar - Scientific Reports, 2016 - nature.com
Lymphatic filariasis (Lf) is one of the oldest and most debilitating tropical diseases. Millions
of people are suffering from this prevalent disease. It is estimated to infect over 120 million …

Novel vaccine design based on genomics data analysis: A review

G Lu, S Shan, B Zainab, Z Ayaz, J He… - Scandinavian …, 2021 - Wiley Online Library
Modification of pathogenic strains with the passage of time is responsible for evolution in the
timeline of vaccine development for last 30 years. Recent advancements in computational …

Modeling novel putative drugs and vaccine candidates against tick-borne pathogens: A subtractive proteomics approach

A Ali, S Ahmad, A Wadood, AU Rehman, H Zahid… - Veterinary …, 2020 - mdpi.com
Ticks and tick-borne pathogens (TBPs) continuously causing substantial losses to the public
and veterinary health sectors. The identification of putative drug targets and vaccine …

Clostridium-DTDB: a comprehensive database for potential drug targets of Clostridium difficile

A Jadhav, V Ezhilarasan, OP Sharma, A Pan - Computers in biology and …, 2013 - Elsevier
Clostridium difficile is considered to be one of the most important causes of health care-
associated infections currently. The prevalence and severity of C. difficile infection have …

[PDF][PDF] In silico identification of common putative drug targets among the pathogens of bacterial meningitis

M Munikumar, IV Priyadarshini, D Pradhan… - Biochem Anal …, 2012 - m.23michael.com
In Silico Identification of Common Putative Drug Targets among the Pathogens of Bacterial
Meningitis Page 1 Research Article Open Access Munikumar et al., Biochem Anal Biochem …

[PDF][PDF] Subtractive proteomics for identification of drug targets in bacterial pathogens: A review

S Maurya, S Akhtar, MH Siddiqui… - International Journal of …, 2020 - academia.edu
The first step in drug and vaccine discovery is the identification of the target. Subtractive
proteomics can be widely used for the process. This approach has been used to find drug …

Structural and functional characterization of a unique hypothetical protein (WP_003901628.1) of Mycobacterium tuberculosis: a computational approach

R Uddin, S Rafi - Medicinal Chemistry Research, 2017 - Springer
Mycobacterium tuberculosis, the causative agent of tuberculosis, has been a serious threat
to public health. The recent emergence of extreme drug-resistant strains further worsened …

Identification of Therapeutic drug Target of Stenotrophomonas maltophilia through subtractive genomic approach and in-silico screening based on 2D similarity …

R Chandela, D Jade, S Mohan… - … Chemistry & High …, 2022 - ingentaconnect.com
Background: Stenotrophomonas maltophilia is a multi-drug resistant, gram-negative
bacterium that causes opportunistic infections and is associated with high morbidity and …