Self-driving laboratories for chemistry and materials science
Self-driving laboratories (SDLs) promise an accelerated application of the scientific method.
Through the automation of experimental workflows, along with autonomous experimental …
Through the automation of experimental workflows, along with autonomous experimental …
Process analytical technologies and self-optimization algorithms in automated pharmaceutical continuous manufacturing
P Liu, H Jin, Y Chen, D Wang, H Yan, M Wu… - Chinese Chemical …, 2024 - Elsevier
The pharmaceutical industry is now paying increased attention to continuous manufacturing.
While the revolution to continuous and automated manufacturing is deepening in most of the …
While the revolution to continuous and automated manufacturing is deepening in most of the …
Continuous flow synthesis of pyridinium salts accelerated by multi-objective Bayesian optimization with active learning
We report a human-in-the-loop implementation of the multi-objective experimental design
via a Bayesian optimization platform (EDBO+) towards the optimization of butylpyridinium …
via a Bayesian optimization platform (EDBO+) towards the optimization of butylpyridinium …
A machine learning-enabled process optimization of ultra-fast flow chemistry with multiple reaction metrics
Discovering the optimum process parameters of ultra-fast reactions, such as lithium–
halogen exchange reactions, is typically achieved by time and resource inefficient methods …
halogen exchange reactions, is typically achieved by time and resource inefficient methods …
Robotic platform for accelerating the high-throughput study of silver nanocrystals in sensitive/selective Hg2+ detection
Colorimetric determination of trace mercury ions (Hg 2+) with high reproducibility and
sensitivity is urgently required for water safety and environmental monitoring. Herein, an …
sensitivity is urgently required for water safety and environmental monitoring. Herein, an …
Autonomous closed-loop photochemical reaction optimization for the synthesis of various angiotensin II receptor blocker molecules
Optimization is gaining huge attention in industries like pharmaceuticals, fine chemicals, and
petrochemicals to maximize reaction yield, minimize waste, and improve process efficiency …
petrochemicals to maximize reaction yield, minimize waste, and improve process efficiency …
[HTML][HTML] Chaotic-flow-driven mixing in T-and V-shaped micromixers
T-and V-shaped (or arrow-shaped) micromixers enable the control of rapid chemical
reactions by permitting accelerated mixing. Their mixing performance has been extensively …
reactions by permitting accelerated mixing. Their mixing performance has been extensively …
Self-optimizing Bayesian for continuous flow synthesis process
The integration of artificial intelligence (AI) and chemistry has propelled the advancement of
continuous flow synthesis, facilitating program-controlled automatic process optimization …
continuous flow synthesis, facilitating program-controlled automatic process optimization …
Efficient multi-objective Bayesian optimization of gas–liquid photochemical reactions using an automated flow platform
S Desimpel, J Dijkmans, KPL Kuijpers… - Chemical Engineering …, 2024 - Elsevier
We developed an automated platform capable of performing photochemical gas–liquid
reactions. The platform was augmented with a state-of-the-art Bayesian optimization …
reactions. The platform was augmented with a state-of-the-art Bayesian optimization …
DigiChemTree enables programmable light-induced carbene generation for on demand chemical synthesis
The reproducibility of chemical reactions, when obtaining protocols from literature or
databases, is highly challenging for academicians, industry professionals and even now for …
databases, is highly challenging for academicians, industry professionals and even now for …