The identification and functional annotation of RNA structures conserved in vertebrates

SE Seemann, AH Mirza, C Hansen… - Genome …, 2017 - genome.cshlp.org
Structured elements of RNA molecules are essential in, eg, RNA stabilization, localization,
and protein interaction, and their conservation across species suggests a common …

Translational co-regulation of a ligand and inhibitor by a conserved RNA element

A Zaucker, A Nagorska, P Kumari, N Hecker… - Nucleic acids …, 2018 - academic.oup.com
In many organisms, transcriptional and post-transcriptional regulation of components of
pathways or processes has been reported. However, to date, there are few reports of …

Relative Information Gain: Shannon entropy-based measure of the relative structural conservation in RNA alignments

M Pietrosanto, M Adinolfi, A Guarracino… - NAR genomics and …, 2021 - academic.oup.com
Structural characterization of RNAs is a dynamic field, offering many modelling possibilities.
RNA secondary structure models are usually characterized by an encoding that depicts …

Multiple sequence alignments enhance boundary definition of RNA structures

R Sabarinathan, C Anthon, J Gorodkin, SE Seemann - Genes, 2018 - mdpi.com
Self-contained structured domains of RNA sequences have often distinct molecular
functions. Determining the boundaries of structured domains of a non-coding RNA (ncRNA) …

NetREX: Network Rewiring using EXpression-Towards Context Specific Regulatory Networks

Y Wang, DY Cho, H Lee, J Fear, B Oliver… - arXiv preprint arXiv …, 2017 - arxiv.org
Understanding gene regulation is a fundamental step towards understanding of how cells
function and respond to environmental cues and perturbations. An important step in this …