Mesenchymal stem cells for neurological disorders

A Andrzejewska, S Dabrowska, B Lukomska… - Advanced …, 2021 - Wiley Online Library
Neurological disorders are becoming a growing burden as society ages, and there is a
compelling need to address this spiraling problem. Stem cell‐based regenerative medicine …

Mesenchymal stem cell perspective: cell biology to clinical progress

MF Pittenger, DE Discher, BM Péault… - NPJ Regenerative …, 2019 - nature.com
The terms MSC and MSCs have become the preferred acronym to describe a cell and a cell
population of multipotential stem/progenitor cells commonly referred to as mesenchymal …

Bone marrow mesenchymal stem cells: Aging and tissue engineering applications to enhance bone healing

H Lin, J Sohn, H Shen, MT Langhans, RS Tuan - Biomaterials, 2019 - Elsevier
Bone has well documented natural healing capacity that normally is sufficient to repair
fractures and other common injuries. However, the properties of bone change throughout …

Mesenchymal stem cells for chronic wound healing: current status of preclinical and clinical studies

YZ Huang, M Gou, LC Da, WQ Zhang… - Tissue Engineering Part …, 2020 - liebertpub.com
Healing skin wounds with anatomic and functional integrity, especially under chronic
pathological conditions, remain an enormous challenge. Due to their outstanding …

Brain pericytes as mediators of neuroinflammation

J Rustenhoven, D Jansson, LC Smyth… - Trends in …, 2017 - cell.com
Brain pericytes are perivascular cells that regulate capillary function, and this localization
puts them in a pivotal position for the regulation of central nervous system (CNS) …

Immunoprivileged no more: measuring the immunogenicity of allogeneic adult mesenchymal stem cells

AK Berglund, LA Fortier, DF Antczak… - Stem cell research & …, 2017 - Springer
Background Autologous and allogeneic adult mesenchymal stem/stromal cells (MSCs) are
increasingly being investigated for treating a wide range of clinical diseases. Allogeneic …

[HTML][HTML] Multicellular crosstalk between exosomes and the neurovascular unit after cerebral ischemia. Therapeutic implications

AM Zagrean, DM Hermann, I Opris, L Zagrean… - Frontiers in …, 2018 - frontiersin.org
Restorative strategies after stroke are focused on the remodeling of cerebral endothelial
cells and brain parenchymal cells. The latter, ie, neurons, neural precursor cells and glial …

[PDF][PDF] Mesenchymal stem and stromal cells harness macrophage-derived amphiregulin to maintain tissue homeostasis

JH Ko, HJ Kim, HJ Jeong, HJ Lee, JY Oh - Cell reports, 2020 - cell.com
The cross-talk between mesenchymal stem and stromal cells (MSCs) and macrophages is
critical for the restoration of tissue homeostasis after injury. Here, we demonstrate a pathway …

Vascularization in tissue engineering: fundamentals and state-of-art

G Yang, B Mahadik, JY Choi… - Progress in Biomedical …, 2020 - iopscience.iop.org
Vascularization is among the top challenges that impede the clinical application of
engineered tissues. This challenge has spurred tremendous research endeavor, defined as …

Higher pericyte content and secretory activity of microfragmented human adipose tissue compared to enzymatically derived stromal vascular fraction

B Vezzani, I Shaw, H Lesme, L Yong… - Stem cells …, 2018 - academic.oup.com
Autologous adipose tissue is used for tissue repletion and/or regeneration as an intact
lipoaspirate or as enzymatically derived stromal vascular fraction (SVF), which may be first …