Polymeric particle-based therapies for acute inflammatory diseases

ER Brannon, MV Guevara, NJ Pacifici, JK Lee… - Nature Reviews …, 2022 - nature.com
Acute inflammation is essential for initiating and coordinating the body's response to injuries
and infections. However, in acute inflammatory diseases, inflammation is not resolved but …

Nanomaterials applied in wound healing: Mechanisms, limitations and perspectives

M Wang, X Huang, H Zheng, Y Tang, K Zeng… - Journal of Controlled …, 2021 - Elsevier
Internal and external factors cause various types of wounds on the skin. Infections,
nonhealing chronic wounds, and aesthetic and functional recovery all cause challenges for …

Hemostatic agents for prehospital hemorrhage control: a narrative review

HT Peng - Military Medical Research, 2020 - Springer
Hemorrhage is the leading cause of preventable death in combat trauma and the secondary
cause of death in civilian trauma. A significant number of deaths due to hemorrhage occur …

[HTML][HTML] Applications of injectable hemostatic materials in wound healing: principles, strategies, performance requirements, and future perspectives

H Wang, L Yang - Theranostics, 2023 - ncbi.nlm.nih.gov
Uncontrolled traumatic bleeding can lead to death due to excessive blood loss within
minutes. Early intervention is crucial to save lives, making timely and effective hemostasis is …

Biomaterials for hemostasis

A Simpson, A Shukla, AC Brown - Annual review of biomedical …, 2022 - annualreviews.org
Uncontrolled bleeding is a major problem in trauma and emergency medicine. While
materials for trauma applications would certainly find utility in traditional surgical settings, the …

A biomimetic platelet based on assembling peptides initiates artificial coagulation

PP Yang, K Zhang, PP He, Y Fan, XJ Gao, X Gao… - Science …, 2020 - science.org
Platelets play a critical role in the regulation of coagulation, one of the essential processes in
life, attracting great attention. However, mimicking platelets for in vivo artificial coagulation is …

A review of treatments for non-compressible torso hemorrhage (NCTH) and internal bleeding

C Hong, BD Olsen, PT Hammond - Biomaterials, 2022 - Elsevier
Non-compressible torso hemorrhage (NCTH) is associated with significant mortality in
preventable deaths, both in the field and in civilian settings. Current management strategies …

Polyester Nanoparticles and Polyurethane Nanocapsules Deliver Pirfenidone To Reduce Fibrosis and Scarring

S Liu, T Ale, V Kehinde, T Ale, HC Wang… - … Biomaterials Science & …, 2023 - ACS Publications
Pirfenidone has been shown to reduce fibrosis and modulate inflammation associated with
conditions from pulmonary fibrosis to rheumatoid arthritis. It may also be useful for ocular …

Modulating nanoparticle size to understand factors affecting hemostatic efficacy and maximize survival in a lethal inferior vena cava injury model

C Hong, O Alser, A Gebran, Y He, W Joo… - ACS …, 2022 - ACS Publications
Intravenous nanoparticle hemostats offer a potentially attractive approach to promote
hemostasis, in particular for inaccessible wounds such as noncompressible torso …

Human clinical relevance of the porcine model of pseudoallergic infusion reactions

J Szebeni, R Bawa - … , Medical Microbiology, COVID-19, and Big …, 2021 - taylorfrancis.com
Infusion reactions, ie, acute hypersensitivity reactions induced by intravenously
administered drugs and certain other compounds represent an old, yet unsolved immune …