The lack of efficient therapeutic options for many severe disorders including cancer spurs
demand for improved drug delivery technologies. Nanoscale drug delivery systems based …

Cartilage tissue is under extensive investigation in tissue engineering and regenerative
medicine studies because of its limited regenerative potential. Currently, many scaffolds are …

Cartilage injuries are escalating worldwide, particularly in aging society. Given its limited self-
healing ability, the repair and regeneration of damaged articular cartilage remain formidable …

Abstract Purpose of Review To review the current basic science and clinical literature on
mesenchymal stem cell (MSC) therapy for articular cartilage defects and osteoarthritis of the …

Osteochondral defect regeneration was a great challenge because of limited self-repaired
ability for its sophisticated hierarchical inner structure. Hereon, the bi-layer hydrogel with …

The SOX family plays a vital role in determining the fate of cells and has garnered attention
in the fields of cancer research and regenerative medicine. It also shows promise in the …

Introduction Cartilage regeneration and restoration is a major topic in orthopedic research
as cartilaginous degeneration and damage is associated with osteoarthritis and joint …

Biomimetic three-layered monolithic scaffold (TLS) intended for treatment of osteochondral
defects was fabricated by using freeze drying method. The multilayered material was …

Tissue engineering and regenerative medicine (TERM) has caused a revolution in present
and future trends of medicine and surgery. In different tissues, advanced TERM approaches …

A porcine calvaria defect study was carried out to investigate the bone repair potential of
three‐dimensional (3D)‐printed poly‐ε‐caprolactone (PCL) scaffolds embedded with …