Burkholderia cepacia Complex Bacteria: a Feared Contamination Risk in Water-Based Pharmaceutical Products

M Tavares, M Kozak, A Balola… - Clinical microbiology …, 2020 - Am Soc Microbiol
Burkholderia cepacia (formerly Pseudomonas cepacia) was once thought to be a single
bacterial species but has expanded to the Burkholderia cepacia complex (Bcc), comprising …

[HTML][HTML] Burkholderia cenocepacia in cystic fibrosis: epidemiology and molecular mechanisms of virulence

P Drevinek, E Mahenthiralingam - Clinical Microbiology and Infection, 2010 - Elsevier
Burkholderia cepacia complex (Bcc) bacteria have gained notoriety as pathogens in cystic
fibrosis (CF) because they are difficult to identify and treat, and also have the ability to …

The various lifestyles of the Burkholderia cepacia complex species: a tribute to adaptation

L Vial, A Chapalain, MC Groleau… - Environmental …, 2011 - Wiley Online Library
Summary The Burkholderia cepacia complex (Bcc) is composed of 17 closely related
species. These bacteria are widely but heterogeneously distributed in the natural …

Pathogenicity, virulence factors, and strategies to fight against Burkholderia cepacia complex pathogens and related species

JH Leitão, SA Sousa, AS Ferreira, CG Ramos… - Applied Microbiology …, 2010 - Springer
Abstract The Burkholderia cepacia complex (Bcc) is a group of 17 closely related species of
the β-proteobacteria subdivision that emerged in the 1980s as important human pathogens …

Reducing virulence of the human pathogen Burkholderia by altering the substrate specificity of the quorum-quenching acylase PvdQ

G Koch, P Nadal-Jimenez, CR Reis… - Proceedings of the …, 2014 - National Acad Sciences
The use of enzymes to interfere with quorum sensing represents an attractive strategy to
fight bacterial infections. We used PvdQ, an effective quorum-quenching enzyme from …

Extractive fermentation for improved production and recovery of lipase derived from Burkholderia cepacia using a thermoseparating polymer in aqueous two-phase …

PL Show, CP Tan, MS Anuar, A Ariff, YA Yusof… - Bioresource …, 2012 - Elsevier
An extractive fermentation technique was developed using a thermoseparating reagent to
form a two-phase system for simultaneous cell cultivation and downstream processing of …

Candidate Essential Genes in Burkholderia cenocepacia J2315 Identified by Genome-Wide TraDIS

YC Wong, M Abd El Ghany, R Naeem, KW Lee… - Frontiers in …, 2016 - frontiersin.org
Burkholderia cenocepacia infection often leads to fatal cepacia syndrome in cystic fibrosis
patients. However, antibiotic therapy rarely results in complete eradication of the pathogen …

Intracellular survival of Burkholderia cepacia complex in phagocytic cells

MA Valvano - Canadian Journal of Microbiology, 2015 - cdnsciencepub.com
Burkholderia cepacia complex (Bcc) species are a group of Gram-negative opportunistic
pathogens that infect the airways of cystic fibrosis patients, and occasionally they infect other …

Linocin and OmpW are involved in attachment of the cystic fibrosis-associated pathogen Burkholderia cepacia complex to lung epithelial cells and protect mice …

S McClean, ME Healy, C Collins, S Carberry… - Infection and …, 2016 - Am Soc Microbiol
Members of the Burkholderia cepacia complex (Bcc) cause chronic opportunistic lung
infections in people with cystic fibrosis (CF), resulting in a gradual lung function decline and …

NMR metabolomics reveal urine markers of microbiome diversity and identify benzoate metabolism as a mediator between high microbial alpha diversity and …

J Hertel, D Fässler, A Heinken, FU Weiß, M Rühlemann… - Metabolites, 2022 - mdpi.com
Microbial metabolites measured using NMR may serve as markers for physiological or
pathological host–microbe interactions and possibly mediate the beneficial effects of …