[HTML][HTML] Unlocking the full potential of SGLT2 inhibitors: expanding applications beyond glycemic control

ME Youssef, G Yahya, MS Popoviciu, S Cavalu… - International Journal of …, 2023 - mdpi.com
The number of diabetic patients has risen dramatically in recent decades, owing mostly to
the rising incidence of type 2 diabetes mellitus (T2DM). Several oral antidiabetic …

Neutrophil extracellular traps: a novel target for the treatment of stroke

Z Zhao, Z Pan, S Zhang, G Ma, W Zhang, J Song… - Pharmacology & …, 2023 - Elsevier
Stroke is a threatening cerebrovascular disease caused by thrombus with high morbidity
and mortality rates. Neutrophils are the first to be recruited in the brain after stroke, which …

[HTML][HTML] Novel insight into cGAS-STING pathway in ischemic stroke: from pre-to post-disease

X Ma, D Xin, R She, D Liu, J Ge, Z Mei - Frontiers in Immunology, 2023 - frontiersin.org
Ischemic stroke, a primary cause of disability and the second leading cause of mortality, has
emerged as an urgent public health issue. Growing evidence suggests that the Cyclic GMP …

[HTML][HTML] Activation of endogenous neurogenesis and angiogenesis by basic fibroblast growth factor-chitosan gel in an adult rat model of ischemic stroke

H Duan, S Li, P Hao, F Hao, W Zhao… - Neural Regeneration …, 2024 - journals.lww.com
Attempts have been made to use cell transplantation and biomaterials to promote cell
proliferation, differentiation, migration, and survival, as well as angiogenesis, in the context …

Collateral blood flow and ischemic core growth

K Seifert, JJ Heit - Translational Stroke Research, 2023 - Springer
Abstract Treatment of a large vessel occlusion in the acute ischemic stroke setting focuses
on vessel recanalization, and endovascular thrombectomy results in favorable outcomes in …

[HTML][HTML] Succinylation modification: a potential therapeutic target in stroke

J Lian, W Liu, Q Hu, X Zhang - Neural Regeneration Research, 2024 - journals.lww.com
Stroke is a leading cause of mortality and disability worldwide. Ischemic cell death triggered
by the compromised supply of blood oxygen and glucose is one of the major …

Gallic acid-based hydrogels for phloretin intestinal release: a promising strategy to reduce oxidative stress in chronic diabetes

R Cassano, F Curcio, R Sole, S Mellace, S Trombino - Molecules, 2024 - mdpi.com
Diabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia caused by
abnormalities in insulin secretion and/or action. In patients with diabetes, complications such …

[HTML][HTML] Mitochondrial transplantation confers protection against the effects of ischemic stroke by repressing microglial pyroptosis and promoting neurogenesis

L Sun, Z Zhao, J Guo, Y Qin, Q Yu, X Shi… - Neural regeneration …, 2024 - journals.lww.com
Transferring healthy and functional mitochondria to the lateral ventricles confers
neuroprotection in a rat model of ischemia-reperfusion injury. Autologous mitochondrial …

[HTML][HTML] Emerging strategies for nerve repair and regeneration in ischemic stroke: neural stem cell therapy

S Wang, Q He, Y Qu, W Yin, R Zhao… - Neural Regeneration …, 2024 - journals.lww.com
Ischemic stroke is a major cause of mortality and disability worldwide, with limited treatment
options available in clinical practice. The emergence of stem cell therapy has provided new …

[HTML][HTML] Alleviation of Neuronal Cell Death and Memory Deficit with Chungkookjang Made with Bacillus amyloliquefaciens and Bacillus subtilis Potentially through …

T Zhang, MS Ryu, X Wu, HJ Yang, SJ Jeong, JW Seo… - Foods, 2021 - mdpi.com
Short-term fermented soybeans (chungkookjang) with specific Bacillus (B.) spp. have anti-
obesity, antidiabetic, and anti-stroke functions. We examined the hypothesis that the long …