Effective clinical methods for large bone defects are not yet available on account of the
complex intrinsic structure and mechanical characteristics of natural bone tissue. It remains …

Articular cartilage is critical for knee joint motion as a connective tissue to disperse loads
and resist high-stress loadings. However, due to the lack of vascular, neural, and lymphatic …

Osteochondral (OC) defects pose an enormous challenge with no entirely satisfactory repair
strategy to date. Herein, a 3D printed gradient hydrogel scaffold with a similar structure to …

Currently, osteochondral defects frequently cause limited motion and impaired function of
the joint, leading to serious healthcare problems, and it is still very challenging to realize the …

Digital light processing (DLP) 3D printing has been utilized to fabricate controlled porous β-
tricalcium phosphate (β-TCP) scaffolds, which promote cell adhesion and angiogenesis …

Repairing osteochondral defects is a considerable challenge because it involves the
breakdown of articular cartilage and underlying bone. Traditional hydrogels with a …

Due to the increasing aging population and the high probability of sport injury among young
people nowadays, it is of great demand to repair/regenerate diseased/defected …

The use of biomimetic scaffolds for bone tissue engineering has been studied for a long
time. Biomimetic scaffolds can assist and accelerate bone regeneration that is similar to that …

Osteochondral defect regeneration was a great challenge because of limited self-repaired
ability for its sophisticated hierarchical inner structure. Hereon, the bi-layer hydrogel with …

Regenerative engineering holds the potential to treat clinically pervasive osteochondral
defects (OCDs). In a synthetic materials-guided approach, the scaffold's chemical and …