Progress and impact of Latin American natural product databases

A Gómez-García, JL Medina-Franco - Biomolecules, 2022 - mdpi.com
Natural products (NPs) are a rich source of structurally novel molecules, and the chemical
space they encompass is far from being fully explored. Over history, NPs have represented a …

Mechanistic aspects of medicinal plants and secondary metabolites against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

K Malekmohammad… - Current pharmaceutical …, 2021 - ingentaconnect.com
Background and Objective: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-
2), a highly pathogenic virus, is responsible for a respiratory disease termed coronavirus …

Rutin is a low micromolar inhibitor of SARS-CoV-2 main protease 3CLpro: Implications for drug design of quercetin analogs

B Rizzuti, F Grande, F Conforti, A Jimenez-Alesanco… - Biomedicines, 2021 - mdpi.com
The pandemic, due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has
stimulated the search for antivirals to tackle COVID-19 infection. Molecules with known …

Potential In Vitro Inhibition of Selected Plant Extracts against SARS-CoV-2 Chymotripsin-Like Protease (3CLPro) Activity

C Guijarro-Real, M Plazas, A Rodríguez-Burruezo… - Foods, 2021 - mdpi.com
Antiviral treatments inhibiting Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) replication may represent a strategy complementary to vaccination to fight the ongoing …

The natural stilbenoid (–)-hopeaphenol inhibits cellular entry of SARS-CoV-2 USA-WA1/2020, B. 1.1. 7, and B. 1.351 variants

I Tietjen, J Cassel, ET Register, XY Zhou… - Antimicrobial Agents …, 2021 - Am Soc Microbiol
Antivirals are urgently needed to combat the global SARS-CoV-2/COVID-19 pandemic,
supplement existing vaccine efforts, and target emerging SARS-CoV-2 variants of concern …

Evaluating the in Vitro Efficacy of Quassinoids from Eurycoma longifolia and Eurycoma harmandiana against Common Cold Human Coronavirus OC43 and SARS …

R Choonong, S Ruangdachsuwan… - Journal of Natural …, 2022 - ACS Publications
Coronavirus disease-2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) infection, has become a pandemic and public health crisis …

A survey on computational methods in discovering protein inhibitors of SARS-CoV-2

Q Liu, J Wan, G Wang - Briefings in Bioinformatics, 2022 - academic.oup.com
The outbreak of acute respiratory disease in 2019, namely Coronavirus Disease-2019
(COVID-19), has become an unprecedented healthcare crisis. To mitigate the pandemic …

[HTML][HTML] Natural and semi-synthetic flavonoid anti-SARS-CoV-2 agents for the treatment of long COVID-19 disease and neurodegenerative disorders of cognitive …

J Melrose, MM Smith - Frontiers in Bioscience-Elite, 2022 - imrpress.com
The aim of this review is to highlight the beneficial attributes of flavonoids, a diverse family of
widely-distributed polyphenolic phytochemicals that have beneficial cell and tissue …

Quinones as promising compounds against respiratory viruses: a review

I Chan-Zapata, R Borges-Argáez, G Ayora-Talavera - Molecules, 2023 - mdpi.com
Respiratory viruses represent a world public health problem, giving rise to annual seasonal
epidemics and several pandemics caused by some of these viruses, including the COVID …

Indian herb-derived phytoconstituent-based antiviral, antimicrobial and antifungal formulation: an oral rinse candidate for oral hygiene and the potential prevention of …

S Sharad, S Kapur - Pathogens, 2021 - mdpi.com
Outbreaks of emerging infectious diseases continue to challenge human health. Novel
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has triggered a global …