[HTML][HTML] The epigenetics of breast cancer
J Jovanovic, JA Rønneberg, J Tost, V Kristensen - Molecular oncology, 2010 - Elsevier
Epigenetic changes can be defined as stable molecular alterations of a cellular phenotype
such as the gene expression profile of a cell that are heritable during somatic cell divisions …
such as the gene expression profile of a cell that are heritable during somatic cell divisions …
Mutual regulation of microRNAs and DNA methylation in human cancers
S Wang, W Wu, FX Claret - Epigenetics, 2017 - Taylor & Francis
ABSTRACT microRNAs (miRNAs) and DNA methylation are the 2 epigenetic modifications
that have emerged in recent years as the most critical players in the regulation of gene …
that have emerged in recent years as the most critical players in the regulation of gene …
HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis
The ten–eleven translocation (TET) family of methylcytosine dioxygenases initiates
demethylation of DNA and is associated with tumorigenesis in many cancers; however, the …
demethylation of DNA and is associated with tumorigenesis in many cancers; however, the …
Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarray-based methylated CpG island recovery assay
De novo methylation of CpG islands is a common phenomenon in human cancer, but the
mechanisms of cancer-associated DNA methylation are not known. We have used tiling …
mechanisms of cancer-associated DNA methylation are not known. We have used tiling …
Advances in mapping the epigenetic modifications of 5‐methylcytosine (5mC), N6‐methyladenine (6mA), and N4‐methylcytosine (4mC)
DNA modification plays a pivotal role in regulating gene expression in cell development. As
prevalent markers on DNA, 5‐methylcytosine (5mC), N6‐methyladenine (6mA), and N4 …
prevalent markers on DNA, 5‐methylcytosine (5mC), N6‐methyladenine (6mA), and N4 …
BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence
Prostate cancer is driven by a combination of genetic and/or epigenetic alterations.
Epigenetic alterations are frequently observed in all human cancers, yet how aberrant …
Epigenetic alterations are frequently observed in all human cancers, yet how aberrant …
Genome-wide analysis of aberrant methylation in human breast cancer cells using methyl-DNA immunoprecipitation combined with high-throughput sequencing
Y Ruike, Y Imanaka, F Sato, K Shimizu, G Tsujimoto - BMC genomics, 2010 - Springer
Background Cancer cells undergo massive alterations to their DNA methylation patterns that
result in aberrant gene expression and malignant phenotypes. However, the mechanisms …
result in aberrant gene expression and malignant phenotypes. However, the mechanisms …
Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity
Silencing of individual genes can occur by genetic and epigenetic processes during
carcinogenesis, but the underlying mechanisms remain unclear. By creating an integrated …
carcinogenesis, but the underlying mechanisms remain unclear. By creating an integrated …
[HTML][HTML] Aldehyde dehydrogenase 1A3 influences breast cancer progression via differential retinoic acid signaling
Aldehyde dehydrogenase (ALDH) 1A enzymes produce retinoic acid (RA), a transcription
induction molecule. To investigate if ALDH1A1 or ALDH1A3-mediated RA signaling has an …
induction molecule. To investigate if ALDH1A1 or ALDH1A3-mediated RA signaling has an …
miRNA gene promoters are frequent targets of aberrant DNA methylation in human breast cancer
L Vrba, JL Muñoz-Rodríguez, MR Stampfer… - PloS one, 2013 - journals.plos.org
miRNAs are important regulators of gene expression that are frequently deregulated in
cancer, with aberrant DNA methylation being an epigenetic mechanism involved in this …
cancer, with aberrant DNA methylation being an epigenetic mechanism involved in this …