Abstract Galectin (Gal)-3 is a β-galactoside-binding lectin emerging as a key player in
cardiac, hepatic, renal, and pulmonary fibrosis and inflammation, respiratory infections …

Galectins are β-galactoside-binding proteins that bind and crosslink molecules via their
sugar moieties, forming signaling and adhesion networks involved in cellular …

Introduction The rising incidence of liver diseases is a worldwide healthcare concern.
However, the therapeutic options to manage chronic inflammation and fibrosis, the …

Galectins are carbohydrate-binding proteins that regulate many cellular functions including
proliferation, adhesion, migration, and phagocytosis. Increasing experimental and clinical …

Cardiovascular disease (CVD) is a global health concern, causing significant morbidity and
mortality. Both lifestyle and genetics influence the development of CVD. It is often diagnosed …

Metabolic alterations within mitochondria, encompassing processes such as autophagy and
energy metabolism, play a pivotal role in facilitating the swift proliferation, invasion, and …

Background Patients with COVID-19 are at increased risk of thrombosis, which is associated
with altered platelet function and coagulopathy, contributing to excess mortality. Objectives …

Background Accumulating epidemiological evidence suggests the association between low
ambient temperature exposure and the risk of ischemic stroke, but the underlying …

Background: IL-37 (interleukin-37), a natural suppressor of innate inflammatory and immune
responses, is increased in patients with myocardial infarction. Platelets play an important …

Post-translational modifications regulate numerous biochemical reactions and functions
through covalent attachment to proteins. Phosphorylation, acetylation and ubiquitination …