Current and emerging strategies to combat antimalarial resistance

C Rasmussen, P Alonso, P Ringwald - Expert Review of Anti …, 2022 - Taylor & Francis
Introduction Since the spread of chloroquine resistance in Plasmodium falciparum in the
1960s, recommendations have been made on how to respond to antimalarial resistance …

[HTML][HTML] Molecular epidemiology of resistance to antimalarial drugs in the Greater Mekong subregion: an observational study

M Imwong, M Dhorda, KM Tun, AM Thu… - The Lancet Infectious …, 2020 - thelancet.com
Summary Background The Greater Mekong subregion is a recurrent source of antimalarial
drug resistance in Plasmodium falciparum malaria. This study aimed to characterise the …

[HTML][HTML] Risk of sudden unexplained death after use of dihydroartemisinin–piperaquine for malaria: a systematic review and Bayesian meta-analysis

XHS Chan, YN Win, LJ Mawer, JY Tan… - The Lancet Infectious …, 2018 - thelancet.com
Background Dihydroartemisinin–piperaquine is an effective and well tolerated artemisinin-
based combination therapy that has been assessed extensively for the prevention and …

Asymptomatic Natural Human Infections With the Simian Malaria Parasites Plasmodium cynomolgi and Plasmodium knowlesi

M Imwong, W Madmanee, K Suwannasin… - The Journal of …, 2019 - academic.oup.com
Abstract Background In Southeast Asia, Plasmodium knowlesi, a parasite of long-tailed
macaques (Macaca fascicularis), is an important cause of human malaria. Plasmodium …

[HTML][HTML] The impact of targeted malaria elimination with mass drug administrations on falciparum malaria in Southeast Asia: a cluster randomised trial

L Von Seidlein, TJ Peto, J Landier, TN Nguyen… - PLoS …, 2019 - journals.plos.org
Background The emergence and spread of multidrug-resistant Plasmodium falciparum in
the Greater Mekong Subregion (GMS) threatens global malaria elimination efforts. Mass …

[HTML][HTML] Effectiveness of reactive focal mass drug administration and reactive focal vector control to reduce malaria transmission in the low malaria-endemic setting of …

MS Hsiang, H Ntuku, KW Roberts, MSK Dufour… - The Lancet, 2020 - thelancet.com
Background In low malaria-endemic settings, screening and treatment of individuals in close
proximity to index cases, also known as reactive case detection (RACD), is practised for …

Ivermectin as a novel complementary malaria control tool to reduce incidence and prevalence: a modelling study

HC Slater, BD Foy, K Kobylinski… - The Lancet Infectious …, 2020 - thelancet.com
Background Ivermectin is a potential new vector control tool to reduce malaria transmission.
Mosquitoes feeding on a bloodmeal containing ivermectin have a reduced lifespan …

[HTML][HTML] Community engagement, social context and coverage of mass anti-malarial administration: Comparative findings from multi-site research in the Greater …

CL Pell, B Adhikari, M Myo Thwin, L Kajeechiwa… - PLoS …, 2019 - journals.plos.org
Background Between 2013 and 2017, targeted malaria elimination (TME), a package of
interventions that includes mass drug administration (MDA)–was piloted in communities with …

Safety, pharmacokinetics, and mosquito‐lethal effects of ivermectin in combination with dihydroartemisinin‐piperaquine and primaquine in healthy adult Thai subjects

KC Kobylinski, P Jittamala… - Clinical …, 2020 - Wiley Online Library
Mass administration of antimalarial drugs and ivermectin are being considered as potential
accelerators of malaria elimination. The safety, tolerability, pharmacokinetics, and mosquito …

[HTML][HTML] Drama as a community engagement strategy for malaria in rural Cambodia

R Lim, R Tripura, TJ Peto, M Sareth… - Wellcome open …, 2017 - ncbi.nlm.nih.gov
Background: Countries in Southeast Asia are working to eliminate multidrug-resistant
falciparum malaria, a major cause of mortality in tropical regions. Malaria is declining but …