Pathogenesis of preterm birth: bidirectional inflammation in mother and fetus
ES Green, PC Arck - Seminars in immunopathology, 2020 - Springer
Abstract Preterm birth (PTB) complicates 5–18% of pregnancies globally and is a leading
cause of maternal and fetal morbidity and mortality. Most PTB is spontaneous and idiopathic …
cause of maternal and fetal morbidity and mortality. Most PTB is spontaneous and idiopathic …
A review on the vagus nerve and autonomic nervous system during fetal development: searching for critical windows
The autonomic nervous system (ANS) is one of the main biological systems that regulates
the body's physiology. Autonomic nervous system regulatory capacity begins before birth as …
the body's physiology. Autonomic nervous system regulatory capacity begins before birth as …
Integrated trajectories of the maternal metabolome, proteome, and immunome predict labor onset
Estimating the time of delivery is of high clinical importance because pre-and postterm
deviations are associated with complications for the mother and her offspring. However …
deviations are associated with complications for the mother and her offspring. However …
Cytokine patterns in maternal serum from first trimester to term and beyond
AH Jarmund, GF Giskeødegård, M Ryssdal… - Frontiers in …, 2021 - frontiersin.org
Pregnancy implies delicate immunological balance between two individuals, with constant
changes and adaptions in response to maternal capacity and fetal demands. We performed …
changes and adaptions in response to maternal capacity and fetal demands. We performed …
Multiomic signals associated with maternal epidemiological factors contributing to preterm birth in low-and middle-income countries
Preterm birth (PTB) is the leading cause of death in children under five, yet comprehensive
studies are hindered by its multiple complex etiologies. Epidemiological associations …
studies are hindered by its multiple complex etiologies. Epidemiological associations …
Immune-metabolic adaptations in pregnancy: A potential stepping-stone to sepsis
S Sharma, PRS Rodrigues, S Zaher, LC Davies… - …, 2022 - thelancet.com
Physiological shifts during pregnancy predispose women to a higher risk of developing
sepsis resulting from a maladapted host-response to infection. Insightful studies have …
sepsis resulting from a maladapted host-response to infection. Insightful studies have …
Omics approaches: interactions at the maternal–fetal interface and origins of child health and disease
Immunoperinatology is an emerging field. Transdisciplinary efforts by physicians, physician‐
scientists, basic science researchers, and computational biologists have made substantial …
scientists, basic science researchers, and computational biologists have made substantial …
Data-driven modeling of pregnancy-related complications
A healthy pregnancy depends on complex interrelated biological adaptations involving
placentation, maternal immune responses, and hormonal homeostasis. Recent advances in …
placentation, maternal immune responses, and hormonal homeostasis. Recent advances in …
Perinatal infection, inflammation, preterm birth, and brain injury: A review with proposals for future investigations
JD Reiss, LS Peterson, SN Nesamoney, AL Chang… - Experimental …, 2022 - Elsevier
Preterm newborns are exposed to several risk factors for developing brain injury. Clinical
studies have suggested that the presence of intrauterine infection is a consistent risk factor …
studies have suggested that the presence of intrauterine infection is a consistent risk factor …
Regulatory T cells in pregnancy: it is not all about FoxP3
In pregnancy, the semi-allogeneic fetus needs to be tolerated by the mother's immune
system. Regulatory T cells (Tregs) play a prominent role in this process. Novel technologies …
system. Regulatory T cells (Tregs) play a prominent role in this process. Novel technologies …