Integrins are cell surface receptors for proteins of the extracellular matrix and plasma‐borne
adhesive proteins. Their involvement in diverse pathologies prompted medicinal chemists to …

Since its discovery, arginine vasopressin (AVP) was subjected to several modifications with
the aim of obtaining novel derivatives with increased potency and selectivity for biomedical …

Constrained peptidomimetic scaffolds are of considerable interest for the design of
therapeutically useful analogues of bioactive peptides. We present the single‐step …

Peptidomimetics containing (S)-or (R)-imidazolidin-2-one-4-carboxylate (Imi) have been
obtained by the expedient in-peptide cyclization of (S)-or (R)-α, β-diaminopropionic acid …

Oxytocin is a peptide drug used to induce labor and prevent bleeding after childbirth. Due to
its instability, transport and storage of oxytocin formulations under tropical conditions is …

Kulokekahilide-2 is a potent cytotoxic depsipeptide isolated from the Hawaiian marine
mollusk Philinopsis speciosa. The structure of kulokekahilide-2 was reported to be …

There is much evidence to support the hypothesis that lipids play a role in the interaction of
peptide hormones with their membrane receptors. This interaction through change of …

In this paper, we use NMR spectroscopy and molecular modeling to examine four new
vasopressin analogs modified with α-2-indanylglycine (Igl) at position 2,[L-Igl2] AVP (I),[D …

The study reports the synthesis and biological evaluation of two opioid analogs, a monomer
and a dimer, obtained as products of the solid‐phase, side‐chain to side‐chain cyclization of …

Since its discovery, arginine vasopressin (AVP) was subjected to several modifications with
the aim of obtaining novel derivatives with increased potency and selectivity for biomedical …