Abstract Objective Ischaemia/reperfusion (I/R) injury is defined as the damage to the tissue
which is caused when blood supply returns to tissue after ischaemia. To protect the …

Aims Torsion of the spermatic cord is a common urologic emergency and can lead to
testicular necrosis and infertility. Diacerein (DIA) is interleukin-1b (IL-1b) blocker which has a …

Solid organ transplantation has become a clinical practice after the development of different
immunosuppressive drugs that allowed controlling rejection. The price to be paid for that is …

Progression of chronic kidney disease associated with progressive fibrosis and impaired
tubular epithelial regeneration is still an unmet biomedical challenge because, once chronic …

AIM: To evaluate preventative effects of ischemic preconditioning (IP) in a rat model of
intestinal injury induced by ischemia-reperfusion (IR). METHODS: Male Sprague-Dawley …

Background Intestinal ischemia-reperfusion injury occurs after different surgical treatments,
including intestinal transplantation. This harmful process may have an effect in remote …

Primary objective: Neuroglobin (NGB) is a known neuroprotector and is up-regulated after
ischaemia-hypoxia brain damage. However, no studies have investigated NGB levels after …

The aim of this study was to assess the preventive effects of ischemic preconditioning (IPC)
on ischemia-reperfusion (IR) injury in the sciatic nerve of the rat hind limb. This study …

Background Galactomannan (GAL), a polysaccharide present on the cell wall of several
fungi, has shown an ability to modulate inflammatory responses through the dectin-1 …

The use of animals to gain knowledge and understanding of diseases needs to be reduced
and refined. In the field of intestinal research, because of the complexity of the gut immune …