Biobehavioral pathways and cancer progression: insights for improving well-being and cancer outcomes

A Chang, EK Sloan, MH Antoni… - Integrative cancer …, 2022 - journals.sagepub.com
The relationship between psychosocial factors and cancer has intrigued people for
centuries. In the last several decades there has been an expansion of mechanistic research …

Reprogramming of energy metabolism in response to radiotherapy in head and neck squamous cell carcinoma

A Cruz-Gregorio, I Martínez-Ramírez… - Cancers, 2019 - mdpi.com
Head and neck cancer (HNC) is the sixth cause of cancer-related death worldwide. Head
and neck squamous cells carcinoma (HNSCC) is the most frequent subtype of HNC. The …

Metabolic regulation in HPV associated head and neck squamous cell carcinoma

V Chandel, S Raj, P Kumar, S Gupta, A Dhasmana… - Life sciences, 2020 - Elsevier
Cancer cells exhibit distinct energy metabolic pathways due to multiple oncogenic events. In
normoxia condition, the anaerobic glycolysis (Warburg effect) is highly observed in head …

Targeting Metastasis in Head and Neck Squamous Cell Carcinoma Using Follistatin mRNA Lipid Nanoparticles

V Grigoriev, T Korzun, AS Moses, A Jozic, X Zhu… - ACS …, 2024 - ACS Publications
Metastatic progression significantly reduces survival rates and complicates treatment
strategies in various cancers. Our study introduces an mRNA therapy for metastasis …

Propranolol promotes glucose dependence and synergizes with dichloroacetate for anti-cancer activity in HNSCC

CT Lucido, WK Miskimins, PD Vermeer - Cancers, 2018 - mdpi.com
Tumor cell metabolism differs from that of normal cells, conferring tumors with metabolic
advantages but affording opportunities for therapeutic intervention. Accordingly, metabolism …

Impairment of hypoxia-induced CA IX by beta-blocker propranolol—impact on progression and metastatic potential of colorectal cancer cells

M Barathova, K Grossmannova… - International Journal of …, 2020 - mdpi.com
The coexistence of cancer and other concomitant diseases is very frequent and has
substantial implications for treatment decisions and outcomes. Beta-blockers, agents that …

Highlighting the potential for chronic stress to minimize therapeutic responses to radiotherapy through increased immunosuppression and radiation resistance

M Chen, AK Singh, EA Repasky - Cancers, 2020 - mdpi.com
Simple Summary Stress is an integral part of life and is necessary for proper development
and function of every organ. However, there is growing evidence that prolonged activation of …

Human papillomavirus-related cancers and mitochondria

A Cruz-Gregorio, AK Aranda-Rivera… - Virus research, 2020 - Elsevier
Although it has been established that persistent infection with high risk human
papillomavirus (HR-HPV) is the main cause in the development of cervical cancer, the HR …

[HTML][HTML] HPV E6 regulates therapy responses in oropharyngeal cancer by repressing the PGC-1α/ERRα axis

MK Sannigrahi, P Rajagopalan, L Lai, X Liu, V Sahu… - JCI insight, 2022 - ncbi.nlm.nih.gov
Therapy with radiation plus cisplatin kills HPV+ oropharyngeal squamous cell carcinomas
(OPSCCs) by increasing reactive oxygen species beyond cellular antioxidant capacity. To …

Interactive regulation of laryngeal cancer and neuroscience

Y Hou, X Yang, S Miao, G Qu, H Meng - Biochimica et Biophysica Acta …, 2021 - Elsevier
Nerve fibres are distributed throughout the body along with blood and lymphatic vessels.
The intrinsic morphological characteristics of nerves and the general characteristics of …