An overview of the recent developments in analytical methodologies for determination of COX-2 inhibitors in bulk drugs, pharmaceuticals and biological matrices
An extensive survey of the literature published in various analytical and pharmaceutical
chemistry related journals has been conducted and the instrumental analytical methods …
chemistry related journals has been conducted and the instrumental analytical methods …
Rofecoxib: an update on physicochemical, pharmaceutical, pharmacodynamic and pharmacokinetic aspects
N Ahuja, A Singh, B Singh - Journal of pharmacy and …, 2003 - Wiley Online Library
ABSTRACT Rofecoxib (MK‐966) is a new generation non‐steroidal anti‐inflammatory agent
(NSAID) that exhibits promising anti‐inflammatory, analgesic and antipyretic activity. It …
(NSAID) that exhibits promising anti‐inflammatory, analgesic and antipyretic activity. It …
Carboranyl derivatives of rofecoxib with cytostatic activity against human melanoma and colon cancer cells
A Buzharevski, S Paskaš, MB Sárosi, M Laube… - Scientific Reports, 2020 - nature.com
Owing to the involvement of cyclooxygenase-2 (COX-2) in carcinogenesis, COX-2-selective
inhibitors are increasingly studied for their potential cytotoxic properties. Moreover, the …
inhibitors are increasingly studied for their potential cytotoxic properties. Moreover, the …
Simultaneous Estimation of Paracetamol and Domperidone in Tablets by Reverse Phase HPLC Method.
A Karthik, G Subramanian… - Indian Journal of …, 2007 - search.ebscohost.com
A simple, fast, precise and accurate liquid chromatographic method was developed for the
simultaneous estimation of paracetamol and domperidone in combined dosage forms. This …
simultaneous estimation of paracetamol and domperidone in combined dosage forms. This …
Application of HPLC and HPTLC for the simultaneous determination of tizanidine and rofecoxib in pharmaceutical dosage form
N Kaul, SR Dhaneshwar, H Agrawal, A Kakad… - … of Pharmaceutical and …, 2005 - Elsevier
Two methods are described for the simultaneous determination of tizanidine and rofecoxib
in binary mixture. The first method was based on HPTLC separation of the two drugs …
in binary mixture. The first method was based on HPTLC separation of the two drugs …
Spectrophotometric method for simultaneous estimation of paracetamol and domperidone in tablet formulation
K Kalra, S Naik, G Jarmal… - Asian Journal of Research …, 2009 - indianjournals.com
The development of Vireodt's method for simultaneous estimation of paracetamol and
domperidone involves absorbance measurement at 250 nm and 285 nm corresponding to …
domperidone involves absorbance measurement at 250 nm and 285 nm corresponding to …
Review of the applications of different analytical techniques for coxibs research
M Starek - Talanta, 2011 - Elsevier
An extensive survey of the literature published in analytical and pharmaceutical chemistry
journals has been conducted and analytical methods which were developed and used for …
journals has been conducted and analytical methods which were developed and used for …
Comprehensive study on degradation profile of firocoxib and structural elucidation of its key degradation products
S Adhikari, J Tian, AM Rustum - Journal of Pharmaceutical and Biomedical …, 2023 - Elsevier
Firocoxib is widely used in veterinary medicine as a non-steroidal analgesic and anti-
inflammatory drug substance. Herein, a comprehensive study on the degradation profile of …
inflammatory drug substance. Herein, a comprehensive study on the degradation profile of …
Development and validation of an HPLC method for the impurity and quantitative analysis of etoricoxib
R Hartman, A Abrahim, A Clausen, B Mao… - Journal of liquid …, 2003 - Taylor & Francis
Abstract Etoricoxib (5‐chloro‐6′‐methyl‐3 [4‐(methanesulfonyl) phenyl]‐2, 3′‐bipyridine)
is a highly active and selective cyclo‐oxygenase II inhibitor. A single, stability‐indicating …
is a highly active and selective cyclo‐oxygenase II inhibitor. A single, stability‐indicating …
Mechanism of base-catalyzed autooxidation of corticosteroids containing 20-keto-21-hydroxyl side chain
M Li, B Chen, S Monteiro, AM Rustum - Tetrahedron Letters, 2009 - Elsevier
Corticosteroids and related compounds containing the 20-keto-21-hydroxyl side chain such
as betamethasone, betamethasone 9, 11-epoxide, dexamethasone, and dexamethasone 9 …
as betamethasone, betamethasone 9, 11-epoxide, dexamethasone, and dexamethasone 9 …