An overview of the recent developments in analytical methodologies for determination of COX-2 inhibitors in bulk drugs, pharmaceuticals and biological matrices

RN Rao, S Meena, AR Rao - Journal of pharmaceutical and biomedical …, 2005 - Elsevier
An extensive survey of the literature published in various analytical and pharmaceutical
chemistry related journals has been conducted and the instrumental analytical methods …

Rofecoxib: an update on physicochemical, pharmaceutical, pharmacodynamic and pharmacokinetic aspects

N Ahuja, A Singh, B Singh - Journal of pharmacy and …, 2003 - Wiley Online Library
ABSTRACT Rofecoxib (MK‐966) is a new generation non‐steroidal anti‐inflammatory agent
(NSAID) that exhibits promising anti‐inflammatory, analgesic and antipyretic activity. It …

Carboranyl derivatives of rofecoxib with cytostatic activity against human melanoma and colon cancer cells

A Buzharevski, S Paskaš, MB Sárosi, M Laube… - Scientific Reports, 2020 - nature.com
Owing to the involvement of cyclooxygenase-2 (COX-2) in carcinogenesis, COX-2-selective
inhibitors are increasingly studied for their potential cytotoxic properties. Moreover, the …

Simultaneous Estimation of Paracetamol and Domperidone in Tablets by Reverse Phase HPLC Method.

A Karthik, G Subramanian… - Indian Journal of …, 2007 - search.ebscohost.com
A simple, fast, precise and accurate liquid chromatographic method was developed for the
simultaneous estimation of paracetamol and domperidone in combined dosage forms. This …

Application of HPLC and HPTLC for the simultaneous determination of tizanidine and rofecoxib in pharmaceutical dosage form

N Kaul, SR Dhaneshwar, H Agrawal, A Kakad… - … of Pharmaceutical and …, 2005 - Elsevier
Two methods are described for the simultaneous determination of tizanidine and rofecoxib
in binary mixture. The first method was based on HPTLC separation of the two drugs …

Spectrophotometric method for simultaneous estimation of paracetamol and domperidone in tablet formulation

K Kalra, S Naik, G Jarmal… - Asian Journal of Research …, 2009 - indianjournals.com
The development of Vireodt's method for simultaneous estimation of paracetamol and
domperidone involves absorbance measurement at 250 nm and 285 nm corresponding to …

Review of the applications of different analytical techniques for coxibs research

M Starek - Talanta, 2011 - Elsevier
An extensive survey of the literature published in analytical and pharmaceutical chemistry
journals has been conducted and analytical methods which were developed and used for …

Comprehensive study on degradation profile of firocoxib and structural elucidation of its key degradation products

S Adhikari, J Tian, AM Rustum - Journal of Pharmaceutical and Biomedical …, 2023 - Elsevier
Firocoxib is widely used in veterinary medicine as a non-steroidal analgesic and anti-
inflammatory drug substance. Herein, a comprehensive study on the degradation profile of …

Development and validation of an HPLC method for the impurity and quantitative analysis of etoricoxib

R Hartman, A Abrahim, A Clausen, B Mao… - Journal of liquid …, 2003 - Taylor & Francis
Abstract Etoricoxib (5‐chloro‐6′‐methyl‐3 [4‐(methanesulfonyl) phenyl]‐2, 3′‐bipyridine)
is a highly active and selective cyclo‐oxygenase II inhibitor. A single, stability‐indicating …

Mechanism of base-catalyzed autooxidation of corticosteroids containing 20-keto-21-hydroxyl side chain

M Li, B Chen, S Monteiro, AM Rustum - Tetrahedron Letters, 2009 - Elsevier
Corticosteroids and related compounds containing the 20-keto-21-hydroxyl side chain such
as betamethasone, betamethasone 9, 11-epoxide, dexamethasone, and dexamethasone 9 …