Aging is characterized by a progressive deterioration of physiological integrity, leading to
impaired functional ability and ultimately increased susceptibility to death. It is a major risk …

As a complicated process, aging is characterized by various changes at the cellular,
subcellular and nuclear levels, one of which is epigenetic aging. With increasing awareness …

The pursuit to discover the fundamental biology and mechanisms of aging within the context
of the physical and social environment is critical to designing interventions to prevent and …

The retinal pigment epithelium-photoreceptor interphase is renewed each day in a stunning
display of cellular interdependence. While photoreceptors use photosensitive pigments to …

Background Epigenetic age acceleration (EAA) and epigenetic gestational age acceleration
(EGAA) are biomarkers of physiological development and may be affected by the perinatal …

Melatonin is an important naturally occurring hormone in mammals. Melatonin-mediated
biological effects include the regulation of circadian rhythms, which is important for optimal …

Forensic age estimation is a DNA intelligence tool that forms an important part of Forensic
DNA Phenotyping. Criminal cases with no suspects or with unsuccessful matches in …

Background Cardiovascular health (CVH) was defined by the American Heart Association
as an integrative idealness of seven clinical or lifestyle factors. Based on populations of …

Bazi Bushen (BZBS), a traditional Chinese medicine, has been proven effective in the
treatment of age-related disease in mouse models. However, whether its therapeutic effects …

Both physiological and pathological aging processes induce brain alterations especially
affecting the speed of processing, working memory, conceptual reasoning and executive …