Over the past four decades, research on the natural history of HIV infection has described
how HIV wreaks havoc on human immunity and causes AIDS. HIV host genomic research …

Single nucleotide polymorphisms (SNPs) are the most abundant type of genomic variation
and the most accessible to genotype in large cohorts. However, they individually explain a …

Aims We prospectively assessed and compared the accuracy of cardiovascular risk scores
in people living with HIV (PLWH) and individuals from the general population. Methods and …

Cardiometabolic diseases, such as type 2 diabetes mellitus (DM) and cardiovascular
disease (CVD), are a great health concern. The strategies aimed to increase awareness and …

We tested associations between 13 established genetic variants and type 2 diabetes (T2D)
in 1371 study participants from the Volga-Ural region of the Eurasian continent, and …

Background DNA-methylation has been associated with plasma lipid concentration in
populations of diverse ethnic backgrounds, but epigenome-wide association studies …

Background Women represent a meaningful proportion of new HIV diagnoses, with Black
women comprising 58% of new diagnoses among women. As HIV infection also increases …

Background: Protease inhibitors (PIs) are believed to affect insulin sensitivity. We aimed to
analyze the effect of PIs on insulin sensitivity and the onset of diabetes mellitus (DM) in …

Background Coronary artery disease (CAD) is a leading cause of death among the 38.4
million people with HIV globally. The extent to which cardiovascular polygenic risk scores …

Background People with human immunodeficiency virus (HIV) infection (PWH) are at higher
risk of myocardial infarction (MI) than those without HIV. About half of MIs in PWH are type 2 …