Nonsocial and social cognition in schizophrenia: current evidence and future directions

MF Green, WP Horan, J Lee - World psychiatry, 2019 - Wiley Online Library
Cognitive impairment in schizophrenia involves a broad array of nonsocial and social
cognitive domains. It is a core feature of the illness, and one with substantial implications for …

Cognitive impairment associated with schizophrenia: from pathophysiology to treatment

DC Javitt - Annual Review of Pharmacology and Toxicology, 2023 - annualreviews.org
Cognitive impairment is a core feature of schizophrenia and a major contributor to poor
functional outcomes. Methods for assessment of cognitive dysfunction in schizophrenia are …

Anticholinergic medication burden–associated cognitive impairment in schizophrenia

YB Joshi, ML Thomas, DL Braff… - American Journal of …, 2021 - Am Psychiatric Assoc
Objective: Many psychotropic medications used to treat schizophrenia have significant
anticholinergic properties, which are linked to cognitive impairment and dementia risk in …

Varieties of Self Disorder: A Bio-Pheno-Social Model of Schizophrenia

L Sass, JP Borda, L Madeira, E Pienkos… - Schizophrenia …, 2018 - academic.oup.com
The self-disorder model offers a unifying way of conceptualizing schizophrenia's highly
diverse symptoms (positive, negative, disorganized), of capturing their distinctive …

Psychosis biotypes: replication and validation from the B-SNIP consortium

BA Clementz, DA Parker, RL Trotti… - Schizophrenia …, 2022 - academic.oup.com
Current clinical phenomenological diagnosis in psychiatry neither captures biologically
homologous disease entities nor allows for individualized treatment prescriptions based on …

Memantine effects on electroencephalographic measures of putative excitatory/inhibitory balance in schizophrenia

JL Molina, B Voytek, ML Thomas, YB Joshi… - Biological Psychiatry …, 2020 - Elsevier
Background Abnormalities in cortical excitation and inhibition (E/I) balance are thought to
underlie sensory and information processing deficits in schizophrenia. Deficits in early …

Evolving notions of schizophrenia as a developmental neurocognitive disorder

LJ Seidman, AF Mirsky - Journal of the International …, 2017 - cambridge.org
We review the changing conceptions of schizophrenia over the past 50 years as it became
understood as a disorder of brain function and structure in which neurocognitive dysfunction …

Eye movement characteristics in schizophrenia: A recent update with clinical implications

K Morita, K Miura, K Kasai… - …, 2020 - Wiley Online Library
Eye movements are indispensable for the collection of visual information in everyday life.
Many findings regarding the neural basis of eye movements have been accumulated from …

Hierarchical pathways from sensory processing to cognitive, clinical, and functional impairments in schizophrenia

D Koshiyama, ML Thomas, M Miyakoshi… - Schizophrenia …, 2021 - academic.oup.com
Cognitive impairment is a hallmark of schizophrenia and a robust predictor of functional
outcomes. Impairments are found in all phases of the illness and are only moderately …

Psychosis spectrum illnesses as disorders of prefrontal critical period plasticity

S Vinogradov, MV Chafee, E Lee… - …, 2023 - nature.com
Emerging research on neuroplasticity processes in psychosis spectrum illnesses—from the
synaptic to the macrocircuit levels—fill key gaps in our models of pathophysiology and open …