Clinical and experimental insight into pathophysiology, comorbidity and therapy of absence seizures

V Crunelli, ML Lőrincz, C McCafferty, RC Lambert… - Brain, 2020 - academic.oup.com
Absence seizures in children and teenagers are generally considered relatively benign
because of their non-convulsive nature and the large incidence of remittance in early …

Seizures in children

A Fine, EC Wirrell - Pediatrics in review, 2020 - publications.aap.org
Epilepsy is one of the most common neurologic disorders seen in children, with the highest
incidence in the first year of life. Diagnostic accuracy can be challenging because many …

ILAE definition of the idiopathic generalized epilepsy syndromes: position statement by the ILAE task force on nosology and definitions

E Hirsch, J French, IE Scheffer, A Bogacz, T Alsaadi… - …, 2022 - Wiley Online Library
Abstract In 2017, the International League Against Epilepsy (ILAE) Classification of
Epilepsies described the “genetic generalized epilepsies”(GGEs), which contained the …

ILAE classification of the epilepsies: Position paper of the ILAE Commission for Classification and Terminology

IE Scheffer, S Berkovic, G Capovilla, MB Connolly… - …, 2017 - Wiley Online Library
Summary The International League Against Epilepsy (ILAE) Classification of the Epilepsies
has been updated to reflect our gain in understanding of the epilepsies and their underlying …

Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy

TA Glauser, A Cnaan, S Shinnar, DG Hirtz… - … England Journal of …, 2010 - Mass Medical Soc
Background Childhood absence epilepsy, the most common pediatric epilepsy syndrome, is
usually treated with ethosuximide, valproic acid, or lamotrigine. The most efficacious and …

Cognitive and neurodevelopmental comorbidities in paediatric epilepsy

KC Nickels, MJ Zaccariello, LD Hamiwka… - Nature Reviews …, 2016 - nature.com
Cognitive and behavioural comorbidities are often seen in children with epilepsy, and are
more common and severe in refractory epilepsy. These comorbidities are associated with …

Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy: initial monotherapy outcomes at 12 months

TA Glauser, A Cnaan, S Shinnar, DG Hirtz… - …, 2013 - Wiley Online Library
Purpose: Determine the optimal initial monotherapy for children with newly diagnosed
childhood absence epilepsy (CAE) based on 12 months of double‐blind therapy. Methods …

Childhood absence epilepsy: behavioral, cognitive, and linguistic comorbidities

R Caplan, P Siddarth, L Stahl, E Lanphier, P Vona… - …, 2008 - Wiley Online Library
Purpose: Evidence for a poor psychiatric, social, and vocational adult outcome in childhood
absence epilepsy (CAE) suggests long‐term unmet mental health, social, and vocational …

Psychiatric and medical comorbidity and quality of life outcomes in childhood-onset epilepsy

CB Baca, BG Vickrey, R Caplan, SD Vassar… - Pediatrics, 2011 - publications.aap.org
OBJECTIVE: We compared associations of epilepsy remission status and severity as well as
psychiatric and other comorbidities with child and parent-proxy reports of health-related …

Pretreatment cognitive deficits and treatment effects on attention in childhood absence epilepsy

D Masur, S Shinnar, A Cnaan, RC Shinnar, P Clark… - Neurology, 2013 - AAN Enterprises
Objective: To determine the neurocognitive deficits associated with newly diagnosed
untreated childhood absence epilepsy (CAE), develop a model describing the factorial …