IGF signaling pathway in bone and cartilage development, homeostasis, and disease

X Ruan, X Jin, F Sun, J Pi, Y Jinghu, X Lin… - The FASEB …, 2024 - Wiley Online Library
The skeleton plays a fundamental role in the maintenance of organ function and daily
activities. The insulin‐like growth factor (IGF) family is a group of polypeptide substances …

[HTML][HTML] Analysis of the value and correlation of IGF‑1 with GH and IGFBP‑3 in the diagnosis of dwarfism

Y Wang, H Zhang, M Cao… - Experimental and …, 2019 - spandidos-publications.com
Correlation between the value of insulin‑like growth factor‑1 (IGF‑1) in the diagnosis of
dwarfism and the levels of growth hormone (GH) and insulin‑like growth factor binding …

儿童特发性矮小的诊治进展

倪佳, 辛颖 - 中国中西医结合儿科学, 2018 - zxek.net
特发性矮小是儿童矮小中较为常见的病因, 但由于其病因复杂, 目前又缺乏相关诊断技术等原因,
仍有相当部分病因及发病机制不明确, 所以迄今仍无统一而有效的治疗方案 …

Association of serum components of the GH-IGFs-IGFBPs system with GHR-exon 3 polymorphism in normal and idiopathic short stature children

MG Ballerini, HM Domené, P Scaglia, A Martínez… - Growth Hormone & IGF …, 2013 - Elsevier
Objective To investigate the possible association of circulating components of GH-IGFs-
IGFBPs system with the GHR-exon 3 genotype in normal and idiopathic short stature (ISS) …

Idiopathic short stature and growth hormone sensitivity in prepubertal children

JGB Derraik, HL Miles, V Chiavaroli… - Clinical …, 2019 - Wiley Online Library
Objective We compared growth hormone sensitivity to an insulin‐like growth factor I (IGF‐I)
generation test in children with idiopathic short stature (ISS) and of normal stature (NS) …

Association between insulin‐like growth factor‐1 and relative skeletal maturation: a retrospective cohort study of short children and adolescents

Q Zhao, M Zhang, Y Chu, B Ji, H Pan… - BioMed Research …, 2020 - Wiley Online Library
Objective. Delays in skeletal maturity are related to bone mass and fracture risk in children,
but the factors that determine it are unknown. We aimed to identify the association between …

Etiology of short stature in Indian children and an assessment of the growth hormone-insulin-like growth factor axis in children with idiopathic short stature

A Kumar, A Pal, M Kalaivani, N Gupta… - Journal of Pediatric …, 2018 - degruyter.com
Background Our objectives were to evaluate the etiology of short stature, assess the
prevalence of idiopathic short stature (ISS) and assess the growth hormone (GH)-insulin-like …

特发性矮小生长激素受体外显子3 基因多态性与生长激素轴的关系.

程炳娟, 刘戈力, 李宁, 杨箐岩… - Tianjin Medical …, 2016 - search.ebscohost.com
目的探讨生长激素受体(GHR) 外显子3 基因型与特发性矮小(ISS) 患者生长激素-
胰岛素样生长因子-胰岛素样生长因子结合蛋白(GH-IGFs-IGFBPs) 轴的关系. 方法选取108 …

Bone age in prepubertal children with nonfamilial or familial idiopathic short stature and prepubertal short-stature children born small for gestational age: a …

M Satoh - Clinical Pediatric Endocrinology, 2021 - jstage.jst.go.jp
This retrospective study aimed to clarify the characteristics of bone maturation using
longitudinal data in short-stature prepubertal children. Children with chronological ages …

[PDF][PDF] Relationship between leptin and insulin-like growth factor-1 in children and adolescent with growth hormone deficiency

NT Tahir, HS Ahmed - Mustansiriya Medical Journal, 2014 - iasj.net
Background: Growth hormone deficiency (GHD) is suspected in subjects with short stature
(SS) and reduced growth velocity in whom other causes of poor growth have been excluded …