Exploring the paradox of defense between host and Leishmania parasite
Leishmaniasis, a neglected tropical disease, still remains a global concern for the
healthcare sector. The primary causative agents of the disease comprise diverse …
healthcare sector. The primary causative agents of the disease comprise diverse …
[PDF][PDF] Medicinal plants with antileishmanial activity on parasites responsible for new-world cutaneous leishmaniasis. A systematic review 2018-2022
YY Lozano, SE Giraldo, AC Zapata… - Journal of Pharmacy & …, 2023 - academia.edu
Context: Cutaneous leishmaniasis is a disease of public health importance; treatment is
based on the use of pentavalent antimonials with high toxicity and low efficacy; therefore, its …
based on the use of pentavalent antimonials with high toxicity and low efficacy; therefore, its …
Quinine and chloroquine: Potential preclinical candidates for the treatment of tegumentary leishmaniasis
NRDLP Rossi, SN Fialho, A de Jesus Gouveia… - Acta Tropica, 2024 - Elsevier
Leishmaniasis is an endemic disease in more than 90 countries, constituting a relevant
public health problem. Limited treatment options, increase in resistance, and therapeutic …
public health problem. Limited treatment options, increase in resistance, and therapeutic …
Piplartine-Inspired 3, 4, 5-Trimethoxycinnamates: Trypanocidal, Mechanism of Action, and In Silico Evaluation
CSMB Filho, RR de Menezes, EP Magalhães… - Molecules, 2023 - mdpi.com
Chagas disease (CD) is one of the main neglected tropical diseases that promote relevant
socioeconomic impacts in several countries. The therapeutic options for the treatment of CD …
socioeconomic impacts in several countries. The therapeutic options for the treatment of CD …
Unveiling the anti-echinococcal efficacy of amide-based compounds: An in-silico and in-vitro study
V Chauhan, U Farooq, M Fahmi, A Khan, PK Tripathi - Heliyon, 2024 - cell.com
Cystic echinococcosis (CE) is a significant global public health concern, particularly in
regions where livestock rearing is prevalent. Despite its impact on morbidity and mortality …
regions where livestock rearing is prevalent. Despite its impact on morbidity and mortality …
Toxicity and Teratogenic Potential of Piplartine from Piper tuberculatum Jacq. during Embryonic Development in Mice (Mus musculus)
GR Silva, LTG Miranda, SACA da Silva… - Drugs and Drug …, 2024 - mdpi.com
Piplartine, also known as piperlongumine, is a natural and biologically active amide alkaloid
found in various Piper species within the Piperaceae family. It possesses numerous …
found in various Piper species within the Piperaceae family. It possesses numerous …
Pharmacokinetic Profile of a Drug Repurposing Candidate for the Treatment of Cutaneous Leishmaniasis (in Silico)
AG Branco, NFO Araújo, SN Fialho, MA Silva… - Brazilian Archives of …, 2024 - SciELO Brasil
The calculated or experimental physical-chemical Properties are important for choosing
substances that will be used in the treatment of several diseases by different administration …
substances that will be used in the treatment of several diseases by different administration …
Antileishmanial Activity of Clinanthus milagroanthus S. Leiva & Meerow (Amaryllidaceae) Collected in Peru
Leishmaniasis is a worldwide infectious parasitic disease caused by different species of
protozoa of the genus Leishmania, which are transmitted to animals and humans through …
protozoa of the genus Leishmania, which are transmitted to animals and humans through …
A utilização de Artesunato e Cloroquina como alternativa terapêutica para tratamento de Leishmaniose tegumentar americana: uma revisão
AGB Junior, ÍDG da Silva, SN Fialho… - Research, Society and …, 2022 - rsdjournal.org
Objetivo: Realizar uma revisão dos trabalhos publicados entre 2016 e 2021 com foco no
tratamento de Leishmaniose com o fármaco Artesunato e Cloroquina. Métodos: Trata-se de …
tratamento de Leishmaniose com o fármaco Artesunato e Cloroquina. Métodos: Trata-se de …
Técnicas inovadoras de entrega transdérmica de fármacos na leishmaniose cutânea
SN Fialho, AGB Junior, VM de Oliveira… - Revista Eletrônica …, 2023 - acervomais.com.br
Objetivo: Identificar os estudos que analisaram o uso de distintos sistemas de entrega
transdérmica, tanto para novas substâncias com potencial leishmanicida, quanto para os …
transdérmica, tanto para novas substâncias com potencial leishmanicida, quanto para os …